General practice faces the challenges of an increase in the prevalence of long-term conditions (LTCs) and multimorbidity, coupled with increasing demand and the need for more collaborative partnerships with patients. To address these challenges, I believe we need a fundamental change in our definitions of health and health care, the way we 'do' general practice, and a transformation in our rela...

Increasing air temperatures and associated permafrost thaw in Arctic river watersheds, such as the Mackenzie River catchment, are directly affecting aquatic environment. As a consequence, quantity quality of dissolved organic carbon (DOC) that is transported via into Ocean expected to change. Particularly these remote regions Arctic, monitoring terrigenous fluxes insufficient knowledge distribu...

Bt1 HERBERT A. PE aNs, MALCOLM R. MACKENZIE AND H. HUGH FUDENBERG T HE ASSOCIATION OF HIGH CONCENTRATIONS of certain paraproteins and abnormal bleeding is well recognized, but the mechanism of defective hemostasis is uncertain. Numerous publications, generally restricted to single case reports or to small series of patients, describe a bewildering inconsistency of abnormal findings, some of whi...

We show how to realize two-factor authentication for a Bitcoin wallet employing the two-party ECDSA signature protocol adapted from MacKenzie & Reiter (2004). We also present a prototypic implementation of a Bitcoin wallet that offers both: two-factor authentication and verification over a separate channel. Since we use a smart phone as the second authentication factor, our solution can be used...

Henrique E. Toma* e Koiti Araki Instituto de Química, Universidade de São Paulo, CP 26077, 05513-970 São Paulo SP, Brasil André Luiz Barboza Formiga Instituto de Química, Universidade Estadual de Campinas, CP 6154, 13084-971 Campinas SP, Brasil Anamaria D. P. Alexiou Universidade Presbiteriana Mackenzie, R. da Consolação, 896, 01302-907 São Paulo SP, Brasil Genebaldo S. Nunes Universidade Estad...