A strong focus on Superparamagnetic Iron Oxide Nanoparticles (SPIOs) has been appreciated recently especially for their use in Magnetic Resonance Imaging (MRI). However, some questions are being raised over these particles due to their long-term toxicity related to the production of toxic free iron during their biodegradation. Here we show by Electron Microscopy how SPIOs (P904) (Guerbet, Paris...

Nanooncology, the application of nanobiotechnology to the management of cancer, is currently the most important chapter of nanomedicine. Nanobiotechnology has refined and extended the limits of molecular diagnosis of cancer, for example, through the use of gold nanoparticles and quantum dots. Nanobiotechnology has also improved the discovery of cancer biomarkers, one such example being the sens...

One quarter of all iodinated contrast X-ray clinical imaging studies are now performed on Chronic Kidney Disease (CKD) patients. Unfortunately, the iodine contrast agent used in X-ray is often toxic to CKD patients' weak kidneys, leading to significant morbidity and mortality. Hence, we are pioneering a new medical imaging method, called Magnetic Particle Imaging (MPI), to replace X-ray and CT ...

The aim of this research is to elucidate the size effect of magnetic nanoparticles on the resultant magneto-dielectric properties of polymer nanocomposites at radio frequencies. The block copolymer of [styrene-b-ethylene/butylene-b-styrene] (SEBS) was utilized as a matrix for the templating of magnetic nanoparticles. Surfactant-modified iron oxide (Fe3O4) nanoparticles of various sizes were suc...

We present an experimental model system that enables quantitative assessment of intergranular exchange coupling in CoCrPt-oxide perpendicular magnetic recording media. A thin film structure consisting of a high coercivity CoPt unicrystal layer and a lower coercivity CoPt layer separated by a thin oxide interlayer is used to model perpendicularly magnetized grains separated by oxide grain bounda...

Microreactors have attracted wide attention in the nano- and biotechnology fields because they offer many advantages over standard liquid phase reactions. We report the development of a magnetic microreactor for reliable, fast and efficient surface functionalization of superparamagnetic iron oxide nanoparticles (SPIONs). A comprehensive study of the development process in terms of setup, loadin...

Magnetic particle imaging (MPI) is an emerging medical imaging modality that directly visualizes magnetic particles in a hot-spot like fashion. We recently developed an iron oxide nanoparticle-micelle (ION-Micelle) platform that allows highly sensitive MPI. The goal of this study was to assess the potential of the ION-Micelles for MPI-based detection of thrombi. To this aim, an in vivo carotid ...

a simple and facile method for the preparation offe2+ supported on hydroxyapatite-core-shell-γ-fe2o3 nanoparticles (γ-fe2o3@hap-fe2+ nps) as an environmentally friendly and recyclable green catalyst is described and used for the one-pot synthesis of benzimidazoles and benzoxazole derivatives via reactions between aromatic aldehydes and ortho‐phenylenediamine or ortho‐aminophenol in aqueous medi...