In late mitosis and early G1, replication origins are licensed for subsequent use by loading complexes of the minichromosome maintenance proteins 2-7 (Mcm2-7). The number of Mcm2-7 complexes loaded onto DNA greatly exceeds the number of replication origins used during S phase, but the function of the excess Mcm2-7 is unknown. Using Xenopus laevis egg extracts, we show that these excess Mcm2-7 c...

The aim of this study was to present in detail the clinical steps of the root-membrane technique. This technique combines the benefits of conventional root submergence via intentional maintenance of a root fragment for ridge preservation with those of immediate implant placement for functional rehabilitation of the treated site. A case study of a tooth diagnosed with a horizontal root fracture ...

the telecom services have been recognized the world-over as an important tool for socioeconomic development for a nation and hence telecom infrastructure is treated as a crucial factor to realize the socio-economic objectives in india. accordingly, the department of telecom has been formulating developmental policies for the accelerated growth of the telecommunication services.  bsnl is a wholl...

this paper discusses the performance evaluation and availability analysis of ammonia synthesis unit of a fertilizer plant. the fertilizer plant is a complex and repairable engineering system comprises of various units viz. shell gasification and carbon recovery, desulphurization, co-shift conversion, decarbonation, nitrogen wash and ammonia synthesis etc. one of the most important functionaries...

obesity is one of the health threatening problems and the second preventable mortality factor, the prevalence of which is increasing. the economic burden of obesity is estimated at 2-7% of the total healthcare costs and it is predicted to be top health problem of the world in 2025. therefore, following up obesity and developing effective clinical interventions is a significant measure taken in ...

optimization of maintenance resources to maximize the system availability is a major concern in different manufacturing systems. therefore, a lot of effort is put to construct optimization models to reach the maximum availability level and to reduce the costs of lack of availability. however, despite these efforts, data uncertainty in the real world problems was neglected in proposed models whi...

patients and methods this was a historical cohort study. a total of 1396 patients admitted between march 2011 and march 2012 in 16 mmt clinics (13 private and 3 state clinics) in rafsanjan, entered the study and their retention rate was examined for one year. the patients’ data abstracted from their medical records using checklists and collected by clinics’ staff. data analyses were performed u...

background: nowadays medical equipment plays an important role in the treatment and in the medical education. using outdated preventive maintenance (pm) system may cause problems in the cutting edge medical equipment, nervous system disease’s equipment (in diagnosis and treatment) which are crucial for every medical center. based on above facts we focused on nervous system treat units’ equipmen...

conclusions the major risk factor of hcv infection was injection drug use. the patient’s awareness of his or her hcv status had a minor effect in reduction of illicit drug use and improvement in mmt retention. therefore, adequate counseling is necessary for drug users in mmt clinics in xi’an. background hepatitis c virus (hcv) infection rates in drug users vary among different regions of china....

conclusions the mmt program is an effective intervention to prevent hcv infection transmission, although it is essential to compare its effectiveness with other interventions before implementing it in nationwide. results of the 259 participants, 98.4% (255) were men, the mean age ± sd was 33.1 ± 7.58 years and hcv prevalence was 50%. the studied idus reported lower rate of risky injecting and s...