AIM This study aimed at investigating the anti-invasive activities of α-mangostin on human melanoma SK-MEL-28 and squamous cell carcinoma A-431 cell lines. MATERIALS AND METHODS Cytotoxicity was tested by the crystal violet assay; anti-invasive activity was detected by the wound healing, cell-matrix adhesion, and boyden chamber assays; and gene regulatory effects by qRT-PCR. Treatments were a...

Indonesia has a very abundant production of mangosteen, which places at the 14th largest mangosteen in world. High affects amount peel waste. On other hand, been identified as rich source health benefits and proven to be antibacterial, antifungal, antioxidant, anti-inflammatory, antitumor, anti-carcinogenic. Traditionally, one conventional medicines used wound dressings or infection medicine. I...

Skipjack fish is a prima donna for Sorong City, West Papua fishing communities. In general, the people of City process skipjack into smoked fish. The smoking carried out using traditional techniques where smoke source in direct contact with raw material, thus significantly affecting appearance Using mangosteen rind extract, precipitating before smoked, will give more attractive color and appear...

The maize p1 gene encodes a Myb-homologous regulator of red pigment biosynthesis. To investigate the tissue-specific regulation of the p1 gene, maize plants were transformed with constructs combining promoter and cDNA sequences of two alleles which differ in pigmentation patterns: P1-wr (white pericarp/red cob) and P1-rr (red pericarp/red cob). Surprisingly, all promoter/cDNA combinations produ...

Polyphenol oxidase(PPO) (E.C. number 1.10.3.1) has ubiquitous distribution in almost all living organism. Whereas, peroxidase(POD) (E.C. number 1.11.1) act as hormone regulation and defense mechanism in plants. Keeping in pace with their present-day industrial application, efforts have been made to evaluate the activity of these two enzymes (PPO and POD) using pepper pericarp (Capsicum annuum L...

Abstract Background Biostimulants, such as algae extracts or amino acids, are becoming more common in agriculture because the mentality is to make plants resistant tolerant negative environmental factors, rather than using synthetic chemicals (herbicides, insecticides and fungicides), whose use decreasing year by year, forcing farmers companies develop new environmentally friendly products. Res...