نتایج جستجو برای: map3k1
تعداد نتایج: 174 فیلتر نتایج به سال:
Insulin-like growth factor (IGF)-1 and the type I IGF-1 receptor are important regulators of vascular function that may contribute to cardiovascular disease. We hypothesized that IGF-1 causes endothelial cell dysfunction and expression of neutrophil and monocyte adhesion molecules by enhancing pro-inflammatory cytokine signal transduction. Long-term IGF-1 treatment of endothelial cells potentia...
Glycogen synthase kinase 3beta (GSK3 beta) is implicated in many biological events, including embryonic development, cell differentiation, apoptosis, and insulin response. GSK3 beta has now been shown to induce activation of the mitogen-activated protein kinase kinase kinase MEKK1 and thereby to promote signaling by the stress-activated protein kinase pathway. GSK3 beta-binding protein blocked ...
(MAP2K3, MKK3) is a member of the dual-specificity protein kinase group (MKK) that belongs to the mitogen-activated protein kinase (MAPK) signaling pathway. Following different forms of stressful stimuli and inflammatory cytokines, MKK3 is activated through phosphorylation on serine and threonine residues at sites Ser189 and Thr193 by MKKK proteins (MEKK 1-4) [1]. Activated MKK3 phosphorylates ...
2 Mannan-binding lectin recognizes structures on ischemic reperfused mouse kidneys and is implicated in tissue injury Mette Møller-Kristensen, Weidong Wang, Marieta Ruseva, Steffen Thiel, Søren Nielsen, Kazue Takahashi, Lei Shi, Alan Ezekowitz, Jens Chr. Jensenius, Mihaela Gadjeva. Department of Medical Microbiology and Immunology, Fax: +45 86196128, Tel: +45 89421776, The Water and Salt Resear...
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