نتایج جستجو برای: mas receptor
تعداد نتایج: 608237 فیلتر نتایج به سال:
CD34(+) stem/progenitor cells have been identified as a promising cell population for the autologous cell-based therapies in patients with cardiovascular disease. The counter-regulatory axes of renin angiotensin system, angiotensin converting enzyme (ACE)/Ang II/angiotensin type 1 (AT1) receptor and ACE2/Ang-(1-7)/Mas receptor, play an important role in the cardiovascular repair. This study eva...
Copyright © 2012 Anderson J. Ferreira et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Cardiovascular disease is America's leading health problem and the leading cause of death. One person in three suffers from some form of ...
Defective absorption of acute allergic airway inflammation is involved in the initiation and development chronic asthma. After allergen exposure, there a rapid recruitment macrophages around airways, which promote inflammatory responses. The Ang-(1?7)/Mas receptor axis reportedly plays protective roles various tissue remodeling processes vivo. However, exact role Mas their underlying mechanisms...
Angiotensin-(1-7) [Ang-(1-7)], an endogenous ligand for the G protein-coupled receptor Mas, exerts both vasodilatory and insulin-sensitizing effects. In skeletal muscle, relaxation of precapillary arterioles recruits microvasculature and increases the endothelial surface area available for nutrient and hormone exchanges. To assess whether Ang-(1-7) recruits microvasculature and enhances insulin...
As multi-agent systems (MAS) are used increasingly often to solve larger and more complex problems, distributed simulation is emerging as the only viable approach to cope with the resultant increased scale and complexity of MAS. While different methods have been proposed for distributing these simulations, the problem of interfacing a MAS with these distributed methods remains just as important...
Metabolic syndrome (MetS) is associated with nephropathy. Along with common risk factors such as hypertension and hyperglycemia, adipocytokines released from perirenal adipose tissue (PRAT) are implicated in the pathogenesis of MetS nephropathy. The study was designed to elucidate the adverse effects of PRAT-derived leptin on nephropathy and to determine whether the angiotensin II type 1 recept...
Angiotensin-(1-7) [Ang-(1-7)] is an endogenous, heptapeptide hormone acting through the Mas receptor (MasR), with antiproliferative and antiangiogenic properties. Recent studies have shown that Ang-(1-7) has an antiproliferative action on lung adenocarcinoma cells and prostate cancer cells. In this study, we report that MasR levels were significantly upregulated in nasopharyngeal carcinoma (NPC...
We read with interest the recent article by Takeda et al. (1) suggesting a beneficial role of ACE type 2 (ACE2) in type 2 diabetes. We would like to share our recent observations (2) complementing this work. Takeda et al. showed that lack of ACE2 did not affect baseline glycemia, as reported previously (3), but promoted impaired glucose tolerance and insulin resistance when the mice were fed a ...
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