BACKGROUND Gestational diabetes mellitus (GDM) is associated with maternal and fetal complications. Specific outcomes in previous pregnancies are considered as risk factors for GDM in the consecutive pregnancies. The aim of this study was to evaluate the pregravid risk factors of GDM in multigravid women. METHODS We conducted a retrospective cross sectional study on 114 multigravid women with...

OBJECTIVE Untreated maternal hypothyroidism during pregnancy can have adverse consequences on maternal health and child intelligence quotient (IQ). Our objective was to examine the cost-effectiveness of screening pregnant women for autoimmune thyroid disease. DESIGN We developed a state-transition Markov model and performed a cost-effectiveness analysis of screening pregnant US women, aged 15...

BACKGROUND Exposure to organochlorine compounds (OCs) can alter thyroid function in humans, and hypothyroidism during early life can adversely affect a child's neurodevelopment. OBJECTIVES In this study we aimed to assess the relationship between developmental organochlorine exposures and thyroid function and the relationship between thyroid function and subsequent neurodevelopment. METHODS...

OBJECTIVES Thyroid hormones play an essential role in fetal growth and maternal hypo-thyroidism which leads to cardiovascular deficiency in their offspring. Considering this, we intended to investigate the impact of gestational hypothyroidism on offspring vascular contractibility and possible underlying mechanisms. MATERIALS AND METHODS Hypothyroidism was induced in female rats by administrat...

congenital hypothyroidism is a condition of thyroid hormone deficiency. approximately 1 in 4000 newborn infants has a deficiency of thyroid function. the aim of this study is determination of the prevalence of permanent and transient congenital hypothyroidism (ch) in yazd, iran.from may 2006 to june 2008, 35377 newborns were screened by measuring serum tsh obtained by heel prick. the neonates w...

A workshop entitled, "The Impact of Maternal Thyroid Diseases on the Developing Fetus: Implications for Diagnosis, Treatment, and Screening," was held in Atlanta, Georgia, January 12-13, 2004. This paper reports on the session that examined the prevalence of thyroid dysfunction in reproductive-age women and the factors associated with abnormal function. For this session the following papers wer...

There is a well-known controversy among scientific societies regarding the recommendation to screen for thyroid dysfunction (TD) during pregnancy. Although several studies have shown an association between maternal subclinical hypothyroidism and/or hypothyroxinemia with obstetric problems and/or neurocognitive impairment in the offspring, there is only limited evidence on the possible positive ...

Radioactive iodine (RAI) is used effectively in the treatment of hyperthyroidism and thyroid cancer, but it is contraindicated during pregnancy. RAI treatment during pregnancy can lead to fetal hypothyroidism, mental retardation and increased malignancy risk in the infant. Pregnancy tests must be performed before treatment in all women of reproductive age. However, at times, RAI is being used b...

Background: According to WHO, highest incidence of anaemia is seen in Asia with about half the anaemic women present Indian subcontinent only. Various studies past have reported that iron deficiency hampers thyroid function. The hormones are essential for both foetal and maternal well-being. Our aim was study anemia among pregnant its effect on profile. Methods: In this prospective observationa...