was determined objectively by demonstrating a plateau of oxygen uptake with increasing workloads. Time to reach a plateau of oxygen uptake was normal (2 to 3 minutes) at all workloads. At any given oxygen uptake, cardiac output and hepatic clearance of indocyanine green (ICG) were abnormally low while total arteriovenous (A-V) oxygen difference, heart rate, blood lactate, and ventilation were a...

OBJECTIVE To compare cardiovascular and ventilatory variables in upright versus aero cycle ergometry at submaximal and maximal exercise intensities in untrained cyclists. METHOD Ten physically active men (mean (SD) age 19.1 (1.10) years) who were unfamiliar with aerobars underwent maximal exercise testing and steady state cycling at 50, 100, and 150 W. RESULTS Participants had significantly...

were measured in a separate series of experiments in a subgroup of four subjects (series II). Mean concentration of ethanol in the blood at the end of the experiment was 156 mg/ 100 ml in series I and 125 mg/ 100 ml in series II. Heart rates at rest and during submaximal exercise were higher after ingestion of ethanol, but there was no effect on stroke volume. After ingestion of ethanol cardiac...

Lower limb blood flow, oxygen uptake, and femoral vein O2 content were measured at rest and during maximal bicycle exercise, performed with two legs and one leg, in four normal subjects and in five patients with severe congestive heart failure. While in normal subjects femoral vein blood flow and lower limb vascular conductance were significantly greater during one-leg exercise than during two-...

Objective: Ziziphus jujuba stimulates the release of nitric oxide (NO).  Because NO is involved in cardiovascular regulations, in this study the effects of hydroalcoholic extract of Z. jujuba on cardiovascular responses in acute NG-nitro-L-arginine methyl ester (L-NAME) hypertensive rats were evaluated. Materials and Methods: Rats were divided into 6 group (n=6): 1) saline, 2) L-NAME received (...

BACKGROUND Atrial fibrillation (AF) is associated with impaired exercise capacity. Oxygen uptake (VO2) kinetics determines cardiopulmonary performance during submaximal exercise, which may be impaired in patients with AF. AIM To study oxygen kinetics and cardiopulmonary performance in patients with AF without structural heart disease and the effects of oral sotalol on these parameters. PATI...

Symptom-limited maximal oxygen intake (VO SL) and electrocardiographic responses to multistage treadmill test were determined before and after 3 months of physical training in 14 patients with coronary heart disease. Six patients also had hemodynamic studies done at several submaximal work loads in the upright position before and after training. S-T-segment responses were measured by computer a...