5-Enolpyruvylshikimate-3-phosphate (EPSP) synthase catalyzes the condensation of shikimate 3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form EPSP, a precursor for the aromatic amino acids. This paper examines a recent claim [Studelska, D. R., McDowell, L. M., Espe, M. P., Klug, C. A., and Schaefer, J. (1997) Biochemistry 36, 15555-15560] that the mechanism of EPSP synthase involves two co...

1. ON HAVING A MIND How simple minded can you be? Many philosophers would answer: no more simple than a language-using human being. Many other philosophers, and most cognitive scientists, would allow that mammals, and perhaps birds, possess minds. But few have gone to the extreme of believing that very simple organisms, such as insects, can be genuinely minded. This is the ground that the prese...

apparent coincidence with the positron lines has deepened the mystery of the origin of these pairs. Despite such subsequent discoveries, this splendid review, with its full documentation, will remain useful to orient anyone who wants to study the fundamentals of heavy-ion-atom collision physics. The volume concludes with a pedagogic review of beam-foil spectroscopy by one of its practitioners, ...

Trianthema portulacastrum (common farm weed in tropical countries) contains 21.5 ± 1.2% crude protein, similar to Lucerne with relatively low structural carbohydrate (neutral detergent fibre: 43.6 ± 3.1%). The mineral profile of T. portulacastrum was well above the critical level as far as calcium (0.3%), magnesium (0.2%), iron (50 ppm), copper (8 ppm), zinc (30.0 ppm) and manganese (50 ppm), w...

An animal’s requirements for TM begin while it is in utero, as TM are essential for proper embryonic development and survival (Ashworth and Antipatis, 2001; Hostetler et al., 2003). Moreover, TM deficiencies of the developing fetus carry over into the postnatal period with lesser TM storage in tissues of the neonates, further limiting neonatal growth, development, performance and immunity. Duri...

The energy dependence of the nonradiative electron capture cross-section is discussed in the relativistic domain. A simple analytic expression is obtained for inner-shell transitions using second-order perturbation theory. We have confirmed that the leading-order term is found to have the following energy dependence: σ ∼ E −1 ln 2 E. This is attributed to a combination of kinematic features of ...

Since the suggestion by Epstein, Post and McDowell (1) that renal conservation of Na is conditioned by the degree of filling of some portion of the arterial tree, various investigators (2, 4-6) have presented conflicting data concerning the role of arterial baroreceptors in the control of aldosterone secretion. Barger, Muldowney and Liebowitz (3, 5) have suggested that the moderator reflex, of ...

It is generally agreed that y globulin concentration in spinal fluid is elevated in some 60% of cases of multiple sclerosis (Kabat, Freedman, Murray, and Knaub, 1950; Roboz, Hess, and Forster, 1953; Yahr, Goldensohn, and Kabat, 1954; Ivers, McKenzie, McGuckin, and Goldstein, 1961; Schapira and Park, 1961; Foster and Horn, 1962). Whilst little is known of its origin or direct pathological signif...