Background: Meconium aspiration syndrome is a common cause of respiratory distress in neonates. This study explores the possibility altering course disease by using anti-inflammatory agents to counter chemical and inflammatory pneumonitis caused meconium. The objective determine if inhaled budesonide therapy can alter clinical improve outcome without causing any serious adverse effects. Methods...

Background: Meconium aspiration syndrome (MAS) is one of the common causes neonatal respiratory distress. Overall frequency meconium stained amniotic fluid (MSAF) ranges between 5 to 25%.Methods: Observational study was conducted on 96 newborns over a period year in department pediatrics, Himalayan Institute Medical Sciences, Dehradun, Uttarakhand. All newborns, inborns and outborns with MSAF a...

COVID-19 associated MIS-C like the disease has not been well described in neonates. So this study aimed to alert neonatal community possibility of multisystem inflammatory syndrome children (MIS-C) critically ill neonates born mothers with or without a history SARS-CoV-2 infection exposure. It’s retrospective four cases admitted Dr. DY Patil Medical College NICU. All are from different localiti...

Background: Since the treatment of meconium ileus is very different from other types of intestinal obstruction, it is very important to distinguish these two entities. The aim of this study was to assess sonographic findings to differentiate meconium ileus from other types of obstruction. Methods: This study was performed in Dr. Sheikh and Akbar hospitals, Mashhad Medical University of Science...

Meconium aspiration syndrome (MAS) is meconium-induced respiratory failure of newborns associated with activation of inflammatory and oxidative pathways. For severe MAS, exogenous surfactant treatment is used which improves respiratory functions but does not treat the inflammation. Oxidative process can lead to later surfactant inactivation; hence, surfactant combination with antioxidative agen...

Extracorporeal membrane oxygenation (ECMO) was developed for adults but has been used in neonates as a life-saving rescue therapy for infants with respiratory failure and/or cardiac collapse as a result of congenital diaphragmatic hernia, meconium aspiration syndrome, persistent pulmonary hypertension, or systemic sepsis. ECMO has been proven to increase the survival rate for these diseases. Th...