Meconium peritonitis results from antenatal perforation of the gastrointestinal tract; it presents as gastrointestinal obstruction, intraabdominal masses, or calcification. The presentation with passage of meconium per vagina secondary to meconium peritonitis is rare. We describe the radiologic and surgical findings in a neonate who had passage of meconium per vagina secondary to ileal atresia ...

This study sought to determine the time interval from fetal defecation to membrane staining and subsequent meconium uptake by amnionic macrophages. Pieces of external membranes were fastened to Teflon rings to create a well. The amnionic surface was exposed to meconium and amniotic fluid for 1 to 48 hours and analyzed microscopically for the presence of free meconium and meconium-laden amnionic...

BACKGROUND/PURPOSE Intestinal obstruction is one of the most common reasons for admission to a neonatal surgical unit and frequently is manifest by bilious vomiting. Not all cases of neonatal bilious vomiting are caused by intestinal obstruction. This study aimed to investigate the outcome of neonates with bilious vomiting. METHODS A prospective audit was undertaken of all neonates with a his...

Introduction: meconium is the thick, Green - Black, with a bad odor material,  that founded around the third month of pregnancy in the intestines of fetus. 8 to 15 percent of infants has the evidence of meconium stained fluid at birth. In this study the factors affecting maternal and neonatal meconium-stained amniotic fluid be examined. Methods: This study was done in the Vali-e- asr hospital ...

We developed a new method for an objective assessment of the meconium content in amniotic fluid. By establishing a standard scale through a serial dilution of a known amount of meconium into the amniotic fluid, we developed a new method "mecometer" that can objectively measure the meconium content in meconium-stained amniotic fluid samples. The objectivity and reliability of this mecometer were...

BACKGROUND We previously showed that meconium causes lung cell death by apoptosis and inflammatory cytokine expression. Whether this is due to meconium exposure itself, or meconium related hypoxia remains unclear. OBJECTIVES To elucidate the effects of meconium, saline, milk, hypoxia and hyperoxia induced lung injury. DESIGN/METHODS We studied 5 groups of rabbit pups: (I) normal saline; (II...

Does meconium cause meconium aspiration syndrome (MAS) or is meconium discharge only a marker of fetal hypoxia? This dispute has lasted for centuries, but since the 1960s, detrimental effects of meconium itself on the lungs have been demonstrated in animal experiments. In clinical MAS, persistent pulmonary hypertension of the newborn is the leading cause of death in MAS. Regarding the complex c...