نتایج جستجو برای: mediator domain
تعداد نتایج: 449434 فیلتر نتایج به سال:
Requisite levels of intracellular cholesterol and fatty acids are maintained in part by the sterol regulatory element binding proteins (SREBPs). Three major SREBP isoforms exist; SREBP-1a and SREBP-1c are expressed from overlapping mRNAs, whereas SREBP-2 is encoded by a separate gene. The active forms of SREBP-1a and SREBP-1c differ only at their extreme N termini; SREBP-1c lacks 28 aa present ...
Pakistan has complete its 75 years of independence and, so far, could not achieve many targets to lift the grace and status in world. Its politics is all about individuals influential groups benefits at cost coalition among institutions state. During this actions, judiciary on occasions became a party or victim instead adopting role mediator. It, sometimes pushed into sometime politicized judic...
OBJECTIVES In observational studies, epidemiologists often attempt to estimate the total effect of an exposure on an outcome of interest. However, when the underlying diagram is unknown and limited knowledge is available, dissecting bias performances is essential to estimating the total effect of an exposure on an outcome when mistakenly adjusting for mediators under logistic regression. Throug...
Although melanomas with mutant v-Raf murine sarcoma viral oncogene homolog B1 (BRAF) can now be effectively targeted, there is no molecular target for most melanomas expressing wild-type BRAF. Here, we show that the activation of Pleckstrin homology domain-interacting protein (PHIP), promotes melanoma metastasis, can be used to classify a subset of primary melanomas, and is a prognostic biomark...
Several LIM domain proteins regulate transcription. They are thought to act through their LIM protein-protein interaction domains as adaptors for the recruitment of transcriptional co-regulators. An intriguing example is nTRIP6, the nuclear isoform of the focal adhesion protein TRIP6. nTRIP6 interacts with AP-1 and enhances its transcriptional activity. nTRIP6 is also essential for the transrep...
objective: the present study aimed to review the relationships between procrastination and two self-factors self-efficacy and self-esteem. methods: participants were 140 undergraduates psychology students enrolled in mohagheg ardabili university, ardabil, iran. instruments used for collecting the required data were the student-version of the general procrastination scale (gp-s), general self-ef...
a signaling partner (Su et al., 2002). A closely related function for the collectins is recognition and removal of Denver, Colorado 80262 apoptotic cells (Ogden et al., 2001) wherein the collectin family molecules bind via their globular heads to the apoptotic cell surface and mediate ingestion through a Summary unique form of stimulated macropinocytosis induced by interaction of their collagen...
Query mapping and transformation techniques for problem solving with multiple knowledge servers. of data models as canonical models for federated databases. 15] W. Kent. Solving domain mismatch and schema mismatch problems with an object-oriented database programming language. 27 Much research remains to be done. First, we have focused on three components of the mediation architecture, namely t...
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