A linear accelerator vendor and the AAPM TG-142 report propose that quality assurance testing for image-guided devices such megavoltage cone-beam CT (MV-CBCT) be conducted on a monthly basis. In clinical settings, however, unpredictable errors such as image artifacts can occur even when quality assurance results performed at this frequency are within tolerance limits. Here, we evaluated the ima...

  Introduction: In the present study, we investigated the role of gold-silica shell-core nanoparticle in megavoltage irradiation of MCF7 breast cancer cells.   Materials and Methods: gold-silicon oxide shell-core nanoparticles (NPs) were obtained by conjugation of gold nanoparticle with amine or thiol functionalized silica nanoparticles (AuN@SiO2 and AuS@SiO...

Introduction: We evaluated a dose comparison tool that can be used to evaluate measured and calculated dose distributions(1). The tool can be used to evaluate dose calculation algorithms by comparison against measurements, or calculations against calculations. The tool is based on a generalization of the dose-difference and distance-to-agreement tools recently described by Harms et al.(2) and i...

The past decade has seen a dramatic increase in interest in the use of gold nanoparticles (GNPs) as radiation sensitizers for radiation therapy. This interest was initially driven by their strong absorption of ionizing radiation and the resulting ability to increase dose deposited within target volumes even at relatively low concentrations. These early observations are supported by extensive ex...

Measuring motion in medical imagery becomes more and more important, in particular for object tracking, image registration, and local displacement measurements. Often, the requirements on the measurement precision are high compared to the image quality. Especially in megavoltage X-ray images (portal images), which are used to check the position of patients in high precision radiotherapy, render...

Introduction: Megavoltage X-ray beams are used to treat cervix cancer due to their skin-sparing effect. Preferably, the radiation surface doses should be negligible; however, it increases due to electron contamination produced by various field parameters. Therefore, it is essential to provide proper knowledge about the effect of different field parameters on radiation doses. This study sought t...