In order to tackle the study of DNA repair pathways, physical and chemical agents creating damage, genotoxins, are frequently employed. Despite their utility, effects rarely restricted DNA, therefore simultaneously harm other cell biomolecules. Methyl methanesulfonate (MMS) is an alkylating agent that acts on by preferentially methylating guanine adenine bases. It broadly used both in basic gen...

The aim of the study was to investigate influence original porous silver–containing sorbent on morphofunctional parameters red blood cells during in vitro hemoperfusion. Material and methods. Donor perfused through glass columns filled with a based aluminum oxide, polydimethylsiloxane silver nanoclusters without silver. effect silver-containing change after perfusion sorbents determined by scan...

The type II secretion (T2S) system of Vibrio cholerae is a multiprotein complex that spans the cell envelope and secretes proteins important for pathogenesis as well as survival in different environments. Here we report that, in addition to the loss of extracellular secretion, removal or inhibition of expression of the T2S genes, epsC-N, results in growth defects and a broad range of alteration...