نتایج جستجو برای: membrane degradation

تعداد نتایج: 529888  

Journal: :Petroleum Chemistry 2022

Abstract Amine absorption processes designed to remove acid gases from gas streams generally face a major challenge of solvent degradation. This degradation leads the formation heat-stable salts (HSS), corrosive agents that irreversibly bind free alkanolamine. The present study proposes, for first time, method HSS perstraction using liquid–liquid membrane contactor allows transfer through porou...

Journal: :Journal of The Electrochemical Society 2022

The use of thinner membranes in polymer electrolyte water electrolysis increases the likelihood forming an explosive H 2 /O mixture anode stream. Doping Pt nanoparticles into a Nafion membrane as recombination catalyst effectively lowers hydrogen crossover. Here, we propose additional co-doping cerium-zirconium oxide radical scavenger to mitigate degradation. Our results show over 4-fold reduct...

Journal: :Plant physiology 1980
R J Cooke K Roberts D D Davies

Transfer of Lemna minor fronds to adverse or stress conditions produces a large increase in the rate of protein degradation. Cycloheximide partially inhibits stress-induced protein degradation and also partially inhibits the protein degradation which occurs in the absence of stress. The increased protein degradation does not appear to be due to an increase in activity of soluble proteolytic enz...

Journal: :Current Biology 2012
Coert Margadant Maaike Kreft Dirk-Jan de Groot Jim C. Norman Arnoud Sonnenberg

BACKGROUND Integrins are heterodimeric αβ transmembrane receptors that play key roles in cellular physiology and pathology. Accumulating data indicate that the two NPxY motifs in the cytoplasmic domain of the β1 subunit synergistically promote integrin activation through the binding of talin and kindlin. However, it is unclear how the individual motifs regulate integrin function and trafficking...

2016
Eisuke Itakura Eszter Zavodszky Sichen Shao Matthew L. Wohlever Robert J. Keenan Ramanujan S. Hegde

We investigated how mitochondrial membrane proteins remain soluble in the cytosol until their delivery to mitochondria or degradation at the proteasome. We show that Ubiquilin family proteins bind transmembrane domains in the cytosol to prevent aggregation and temporarily allow opportunities for membrane targeting. Over time, Ubiquilins recruit an E3 ligase to ubiquitinate bound clients. The at...

Journal: :Cardiovascular research 2004
Viviana M Berthoud Peter J Minogue James G Laing Eric C Beyer

Gap junctional proteins, connexins, and gap junctional plaques are short-lived. Three pathways for their degradation have been proposed: (1) misfolded/abnormally oligomerized connexins are retrogradely translocated and degraded by the proteasome through endoplasmic reticulum-associated degradation; (2) connexins (as monomers or oligomers) may traffic directly from an early secretory compartment...

2014
Sarah J. Fletcher Mudassar Iqbal Sara Jabbari Dov Stekel Joshua Z. Rappoport

Tight junctions (TJs) link adjacent cells and are critical for maintenance of apical-basolateral polarity in epithelial monolayers. The TJ protein occludin functions in disparate processes, including wound healing and Hepatitis C Virus infection. Little is known about steady-state occludin trafficking into and out of the plasma membrane. Therefore, we determined the mechanisms responsible for o...

Journal: :Plant physiology 1979
S Yoshida

Freeze-thawing of microsome-enriched membranes from living bark tissues of black locust trees, especially those from less hardy tissues, caused a drastic increase in sensitivity to Ca(2+) and a complete loss of the regulatory action of Mg(2+) in membrane-bound phospholipase D activity with endogenous (membrane-bound) substrates. Also, the freeze-thaw cycle made phospholipase D in these membrane...

2014
Enrico Sciubba

As a solution of high efficiency and clean energy, fuel cell technologies, especially proton exchange membrane fuel cell (PEMFC), have caught extensive attention. However, after decades of development, the performances of PEMFCs are far from achieving the target from the Department of Energy (DOE). Thus, further understanding of the degradation mechanism is needed to overcome this obstacle. Due...

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