This study was conducted to detect quantitative trait loci (QTL) affecting meat quality in an F2 reference population of Korean native pig and Landrace crossbreds. The three-generation mapping population was generated with 411 progeny from 38 F2 fullsib families, and 133 genetic markers were used to produce a sex-average map of the 17 autosomes. The data set was analyzed using least squares Men...

Response by Liu and Sun to Letter Regarding Article, “Plasma Levels of Fatty Acid– Binding Protein 4, Retinol-Binding Protein 4, High-Molecular-Weight Adiponectin, and Cardiovascular Mortality Among Men With Type 2 Diabetes: A 22-Year Prospective Study” In Response: We appreciate Menzaghi et al comments on our prospective cohort analysis on high-molecular-weight adiponectin and cardiovascular d...

BACKGROUND Triglycerides and their lipoprotein transport molecules are risk factors for heart disease. Observational studies have associated elevated levels of serum urate (SU) with triglycerides and risk of heart disease. However, owing to unmeasured confounding, observational studies do not provide insight into the causal relationship between SU and triglyceride. The aim of this study was to ...

Developments in genome-wide association studies and the increasing availability of summary genetic association data have made application of Mendelian randomization relatively straightforward. However, obtaining reliable results from a Mendelian randomization investigation remains problematic, as the conventional inverse-variance weighted method only gives consistent estimates if all of the gen...