OBJECTIVES To determine the level of serum procalcitonin, blood leukocyte count (TLC) and C-reactive protein (CRP) in children with bacterial and non bacterial meningitis and document their efficacy in differential diagnosis. Also described are procalcitonin levels variation during treatment. METHODS From March 2005 to February 2008, we evaluated 38 clinically suspected meningitis patients in...

BACKGROUND Pediatric meningitis remains a common cause of childhood morbidity and mortality in developing countries. Knowledge of the causative organisms in a region is of importance in guiding empiric antibiotic regimes and immunization schedules assisting decisions on primary health-care interventions. METHODS This retrospective review of 557 meningitis cases represents a third pediatric su...

to the discovery of antibiotics, bacterial meningitis was almost invariably fatal: over 95% of individuals developing bacterial meningitis died, and the few individuals surviving infection were neurologically devastated. With the advent of antibiotics, bacterial meningitis became a treatable condition, and the primary objective in the patient with bacterial meningitis became, appropriately, pro...

BACKGROUND Two of the most prevalent causes of severe bacterial meningitis in children, Haemophilus influenzae type B (Hib) and Streptococcus pneumoniae, are preventable by existing vaccines increasingly available in developing countries. Our objective was to estimate the dose-specific effect of Hib and pneumococcal conjugate vaccines (PCV) on childhood meningitis mortality in low-income countr...

Lactate deyhydrogenase intracellular tetramer protein, expressed as five isoenzymes having different distribution in various tissues [2,3]. It is an important indicator of bacterial meningitis [4,5] and it help to differentiate bacterial from non bacterial meningitis [6,7]. Viral meningitis is usually associated with normal or mildly elevated LDH levels, while bacterial meningitis is usually as...

Mollaret meningitis is characterized by three or more episodes of benign recurrent aseptic meningitis in which symptoms and signs resolve spontaneously within two to five days. Severe headache with an acute onset, fever and meningismus are the main clinical features. We report a case of Mollaret meningitis in a seven-year-old girl who presented with four aseptic meningitis episodes in one year.

Penelitian ini bertujuan untuk menyelesaikan model SEIR penyebaran penyakit meningitis menggunakan metode Euler, Heun dan Runge-Kutta orde empat, dimana persamaannya berupa persamaan diferensial nonlinear. Metode penelitian yang digunakan adalah pemrograman komputer simulasi. Dari simulasi, ketiga tersebut menghasilkan penyelesaian dengan perilaku mirip, yaitu semua gambar grafik pada setiap si...

Bacterial meningitis in the African meningitis belt remains 1 of the most serious threats to health. The perceptions regarding meningitis in local populations and the cost of illness for households are not well described. We conducted an anthropologic and economic study in Burkina Faso, in the heart of the meningitis belt. Respondents reported combining traditional and modern beliefs regarding ...

Recurrent meningitis is an uncommon life-threatening condition. Here, the case of a 6-year-old boy is reported who had two episodes of meningitis with an IgG3 subclass deficiency. The boy had aseptic meningitis at the age of 3 years, followed by bacterial meningitis at the age of 4 years. Primary immunoglobulin deficiencies are a group of disorders associated with an increased incidence and/or ...

Group B Streptococcus (GBS) is the major cause of human neonatal infections. A single clone, designated CC17-GBS, accounts for more than 80% meningitis cases, most severe form infection. However, events allowing blood-borne GBS to penetrate brain remain largely elusive. In this study, we identified host transmembrane receptors ?5?1 and ?v?3 integrins as ligands Srr2, a CC17-GBS–specific adhesin...