HAEMOLYTIC streptococci were first subdivided into groups by precipitation of specific carbohydrate (Lancefield, 1933, 1934). It soon became apparent that most serious streptococcal infections were caused by organisms of Group A. Although organisms of Group B were known to cause mastitis in cattle there was little evidence of pathogenic activity in man. Then in 1937 Colebrook & Purdie included ...

The effect of Escherichia coli strains isolated from blood and cerebrospinal fluid of septic infants on plasminogen activation was studied. These strains typically carry a filamentous surface protein, S fimbria, that has formerly been shown to bind to endothelial cells and interact with plasminogen. The. bacteria effectively promoted plasminogen activation by tissue plasminogen activator (t-PA)...

The enterobacteriaceae are of particular importance in infancy as a cause of meningitis. Cooke and Bell (1922) postulated that certain strains of the coli aerogenes group might have a special tendency to invade the meninges, and suggested that full descriptions of the organisms isolated from such cases would be of value. Again, Barrett, Rammelkamp and Worcester (1942) commented on the frequent ...

Brief History of the Present Illness A 6-day-old female with septic shock was admitted to the hospital in the fall. Two days before admission, she had developed a macular rash on her face and extremities that was attributed to a normal newborn rash. She also had difficulty with breastfeeding, and her mother started formula supplementation upon suggestion by her pediatrician. Over the next 48 ho...

Bacterial meningitis remains a serious cause of morbidity and mortality in childhood. Epidemiologic investigations have shown variability in disease risks among different populations and races. In Korea, however, basic epidemiologic information on bacterial meningitis in children is limited. The main purpose of this study was to analyze bacteriologically proven meningitis cases in terms of the ...

conclusions due to the increasing resistance of pathogens to usual empirical antibiotics, it is reasonable to stress upon preventive measures, so that a minimum number of neonates develop sepsis. results coagulase-negative staphylococci (cons) were the most prevalent pathogens isolated from blood specimens in early and late-onset disease. escherichia coli and klebsiella were the most causative ...

Bacterial meningitis is generally a devastating infection of the leptomeninges and underlying subarachnoid cerebrospinal fluid with a high mortality rate, particularly in the perinatal and neonatal infant. This is more worrisome because despite the more available potent antimicrobials and variably effective vaccines, the disease remains a significant cause of morbidity and mortality. Mortality ...

We investigated six cases of enterovirus infection in a neonatal unit. The index patient, a 5-day-old boy, was admitted with aseptic meningitis due to echovirus 30 (E30). Secondary infections with E30 occurred in five babies. Comparison of the complete VP1 sequences showed that the isolates recovered from the index patient and his mother were closely related to those recovered from the five bab...

Chryseobacterium indologenes is a rare cause of infection in infants. The majority of case reports belong to hospitalized infants with indwelling devices. We are presenting a rare case of Chryseobacterium indologenes meningitis in a healthy newborn with no neonatal intensive care unit admissions or indwelling devices. The pathogen is resistant to many antibiotics and the patient was successfull...