Patients with Diabetes Mellitus (DM) have accelerated atherosclerosis, which is the main essential factor contributing to high risk of atherothrombotic events in these patients. Atherothrombotic complications are principal cause morbidity and mortality patients DM. Both atherosclerosis increased thrombotic vascular may result from dyslipidaemia, endothelial dysfunction, platelet hyperreactivity...

INTRODUCTION In Central and Eastern European countries, cardiovascular disorders (CVD) in middle age are much more common than in Western Europe, and it is imperative to understand the causes underlying this excess disease burden. The metabolic syndrome comprises a constellation of metabolic abnormalities that increase the risk of cardiovascular disease. METHODS Data were obtained by structur...

Metabolic syndrome (MetS) is a cluster of metabolic abnormalities that can predispose an individual to a greater risk of developing type-2 diabetes and cardiovascular diseases. The cluster includes abdominal obesity, dyslipidemia, hypertension, and hyperglycemia - all of which are risk factors to public health. While searching for a link among the aforementioned malaises, clues have been focuse...

BACKGROUND Recent studies have suggested that obesity, hyperlipidemia, ischemic heart diseases, metabolic syndrome and hypertension can combine with psoriasis. However, the metabolic comorbidities have not been clearly demonstrated in Korean psoriasis patients. OBJECTIVE The purpose of this study was to analyze the association between psoriasis and metabolic abnormalities including obesity, g...

Polycystic ovary syndrome is a common endocrinopathy characterized by oligo ovulation or anovulation, signs of androgen excess and multiple small ovarian cysts. It includes various metabolic abnormalities: insulin resistance, hyperinsulinemia, impaired glucose tolerance, visceral obesity, inflammation and endothelial dysfunction, hypertension and dyslipidemia. All these metabolic abnormalities ...

BACKGROUND Although the use of androgen deprivation therapy (ADT) has resulted in improved survival in men with advanced prostate cancer, the resulting hypogonadism is associated with profound adverse effects comparable to those found in morbid obesity, being cardiovascular risk among the most lethal. OBJECTIVES Evaluate metabolic syndrome, metabolic abnormalities and cardiovascular risk in p...

This study estimated and compared the prevalence of the Metabolic Syndrome and its individual components in young adults (ages 20-39 years) in the US and Korea using 2003-2004 US and 2005 Korean National Health and Nutrition Examination Survey data. The mean body mass index and rate of metabolic abnormalities in the US were significantly higher than in Korea. The prevalence of the Metabolic Syn...

Polycystic ovary syndrome (PCOS) is associated with insulin resistance. There are also defects in pancreatic beta-cell function in affected women. These abnormalities are heritable. There are post-binding defects in insulin receptor signaling, with selective resistance to insulin's metabolic actions and constitutively activated mitogenic signaling in skeletal muscle. Intrinsic and environmental...

Background: Majority of Burkinabè adults were normal-weight by body mass index (BMI). This study explored gender, the metabolic abnormalities and “metabolic obesity with weight” (MONW) throughout normal BMI quartiles (Q) adults. Methods: We performed a secondary-analysis data from first WHO Stepwise approach to surveillance survey conducted in 2013 Burkina Faso, only between 18.5 ...

White adipose tissue (WAT) asset, in terms of cell number, fat storage capacity and endocrine function, is largely determined in early stages of life and is pivotal for shaping the WAT pro-inflammatory behavior. WAT derived adipokines have been shown to play a main role in several cardio-metabolic abnormalities of obesity. This review focuses on the most recently identified adipokines, namely a...