Symmetric and asymmetric chalcogenides of organic nature are a class organometallic compounds that widely used as intermediates in number reactions, ligands the chemistry coordination compounds, they have wide range biological activity. Diaryl tellurides, which important for formation new carbon-carbon bonds, special area organotelluric compounds. The synthesis representatives this tellurium-co...

The pathway of thiamine biosynthesis in Escherichia coli from its pyrimidine and thiazole moieties involves four enzymes (Y. Nose et al., J. Vitaminol. Kyoto 10:105, 1964): hydroxymethylpyrimidine kinase (EC 2.7.1.49), phosphohydroxymethylpyrimidine kinase (EC 2.7.4.7), thiazole kinase (EC 2.7.1.50), and thiamine phosphate pyrophosphorylase (EC 2.5.1.3). A mutant of E. coli W auxotrophic for th...

The combination of thiazole orange (TO) and thiazole red (TR) as an internal pair of fluorescent DNA base surrogates ("DNA traffic lights") allows us to follow at least two consecutive DNA strand displacements in real time through a distinct fluorescence colour change from green to red and vice versa.

The study of the effectiveness of several potential copper corrosion inhibitors in acidic media was studied. The investigated thiazole derivative functional groups contain heterocyclic atoms such as nitrogen, sulfur, and oxygen. Thiazole derivatives, 5-benzylidene-2,4-dioxotetrahydro-1,3-thiazole (BDT) 5-(4′-isopropylbenzylidene)-2,4-dioxotetrahydro-1,3-thiazole (IPBDT), 5-(3′-thenylidene)-2,4-...

A novel chemoenzymatic one-pot multicomponent synthesis of thiazole derivatives was developed. A series of thiazole derivatives were synthesized with high yields up to 94% under mild enzyme-catalyzed conditions. The blank and control experiments reveal that trypsin from porcine pancreas (PPT) displayed great catalytic activity to promote this reaction and showed a wide tolerance range towards d...

This study aimed for the synthesis of new heterocyclic compounds incorporating sulfamoyl moiety suitable for use as antimicrobial agents via a versatile, readily accessible N-[4-(aminosulfonyl)phenyl]-2-cyanoacetamide (3). The 2-pyridone derivatives were obtained via reaction of cyanoacetamide with acetylacetone or arylidenes malononitrile. Cycloaddition reaction of cyanoacetamide with salicyal...