Aim: A variety of Paracetamol derivatives as mannich bases were prepared through mannich reaction by reacting Paracetamol as compound containing active hydrogen, substituted benzaldehyde, morpholine as secondary amine compound and small amount of conc. HCl as catalyst. A simplistic one-pot method under mild conditions has been developed for the synthesis of all the compounds and they were chara...

anti-microbial effects of the lactic acid bacteria have been studied and proved in various investigations. this investigation aimed to study the anti-yeast effect of two isolated lactic acid bacteria species from “chal” (a product from yogurt) as biological preservatives in doogh. to do so, anti-yeast activity of l. brevis and e. faecium against saccharomyces cerevisiae, kluyveromyces. marxianu...

Yerba mate (Ilex paraguariensis St. Hil.) has been studied for its important biological activities mainly attributed to phenolic compounds. This study evaluated the antimicrobial activity of methanolic and ethanolic extracts of yerba mate against food pathogens, such as Staphylococcus aureus, Listeria monocytogenes, Salmonella Enteritidis and Escherichia coli through minimum inhibitory (MIC) an...

INTRODUCTION Honey has a wide range of antimicrobial activity. All previous studies have considered honey's effect on a single microbe. The present study investigated activity of honey towards a high dose of single or polymicrobial culture. MATERIAL AND METHODS 10 µl specimens of Staphylococcus aureus (S. aureus), Streptococcus pyogenes (S. pyogenes), Escherichia coli (E. coli) and Candida al...

The inhibitory activities of representative beta-lactam compounds, such as penicillins G and N, cephalosporins C and G, clavulanic acid, nocardicin A and thienamycin against Escherichia coli KN-126 and Bacillus megaterium KM peptidoglycan transpeptidases were studied. Their modes of action against E. coli are discussed on the basis of the results and the published binding data for penicillin bi...

Introduction: The chemistry of metal complexes derived from heterocyclic compounds has attracted considerable interest due to the broad range of pharmacological activities of such compounds. The important pathogens such as Escherichia coli, and Staphylococcus aureus are wildly caused many diseases. So antibacterial activity of Zn (Ⅱ), Ni (Ⅱ), Co (Ⅱ) and Cu (Ⅱ) chromone complexes against two kin...

growing interest to use natural preservatives and spices with antimicrobial effects and large amounts of floral bio-residues (92.6 g per 100 g) generated and wasted in the production of saffron spice guided this study  to evaluate  the opportunity to expand the uses of c. sativus flowers (petals and stamens), beyond the spice (dried stigmas). the antibacterial potential of total extracts and di...

Introduction: Antibiotic resistance, especially in Gram-negative uropathogens such as Escherichia coli, is the main barrier to treat urinary tract infection (UTI). In recent years, the dramatically increased resistance of E. coli to quinolones, a group of widely used antibiotics, has become a significant concern. Methods: In this descriptive cross-sectional study, we collected 261 E. coli isola...

The physical and chemical properties of six crude phytase preparations were compared. Four of these enzymes (Aspergillus A, Aspergillus R, Peniophora and Aspergillus T) were produced at commercial scale for the use as feed additives while the other two (E. coli and Bacillus) were produced at laboratory scale. The encoding genes of the enzymes were from different microbial origins (4 of fungal o...