an alternative in vitro approach to drug screening has been the use of human cell cultures for antiviral agents and microbial cell cultures for the assessment of the carcinogenic potential of selected compounds. a number of protozoan species have been also used as drug screens for anti-protozoal agents. the ciliated protozoan tetrahymena pyriformis species has been widely utilised as a drug scr...

background: essential oils of medicinal plants such as chamomile are very complex natural mixtures which can contain compounds at quite different concentrations and some of their components have antioxidant and antimicrobial activities in foodstuff. objective: the antioxidant and antimicrobial effects of chamomile essential oil in cake preparation were evaluated during 75 days of storage. metho...

Biofilm is an assemblage of the microbial cells that is irreversibly associated with a surface and usually enclosed in a matrix of polysaccharide material. Biofilm is composed primarily of microbial cells and extracellular polymeric substance (EPS). Extracellular polymeric matrix plays various roles in structure and function of different biofilm communities. Adhesion to the surface provides con...

Microbial volatile organic compounds (MVOCs) are produced by a wide array of microorganisms ranging from bacteria to fungi. A growing body of evidence indicates that MVOCs are ecofriendly and can be exploited as a cost-effective sustainable strategy for use in agricultural practice as agents that enhance plant growth, productivity, and disease resistance. As naturally occurring chemicals, MVOCs...

Knowing the type of infections in different geographical regions may help to prevent the distribution of diseases. Vaccines, repellents, mosquito nets and clothes are recommended for preventing the increase of infectious diseases. There are different types of climate and geographical items around the world which determine the kind of skin infections. Travelers' skin diseases are recognized as s...

Some new b-lactams bearing biologically important morpholine ring have been synthesized by acylation of amino b-lactams in the presence of morpholine-4-carbonyl chloride. These novel β-lactams were prepared under mild reaction conditions without any solvent in short reaction times. Their biological activities have been examined against microbial agents such as Staphylococcus aureus (S. aureus),...

Cultured skin substitutes have become therapeutic alternatives for treatment of acute and chronic skin wounds, but all models of these substitutes are avascular and susceptible to microbial destruction during vascularization. To develop a practical management protocol for increased survival of skin substitutes, experimental wounds were contaminated with Pseudomonas aeruginosa and treated with a...

The key factor in the production of pulp and periapical inflammation is represented by the presence of bacteria in the root canal system and the outcoming toxins. Bacterial biofilm is identifiable in the various areas of the endodontic space, but due to the complexity of the internal anatomy of the root canal, bacteria removing is yet difficult to obtain, a particularly important step for treat...

Ecologically sustainable agricultural practices are essential to ensure food security, and efficient agriculturally beneficial microbes (microbial inoculants) are playing potential role in sustainable crop production due to their immense plant growth promoting attributes, better adaptability to survival under stresses, and other uses that result in attenuating the pesticides/fertilizers use in ...

There is an urgent need to develop new technologies to address the problem of soil remediation in high-latitude regions. A field study was initiated in January 1997 in two contaminated soils in Terre Adélie (Antarctica) with the objective of determining the long-term effectiveness of two bioremediation agents on total and hydrocarbondegrading microbial assemblages under severe Antarctic conditi...