The present study was done to scrutinize the possible relation between infective genes and antimicrobial resistance in Enterococcus faecalis and Enterococcus faecium. Considering the fact that the presence of recognized infective determinants among clinical isolates may promote the emergence of infections and persistence of Enterococci in hospital settings, which can lead to an increase in anti...

Biofilms are at the root of many infections largely because they are much more antibiotic resistant than their planktonic counterparts. Antibiotics that target the biofilm phenotype are desperately needed, but there is still no standard method to assess biofilm drug susceptibility. Staphylococcus epidermidis ATCC 35984 biofilms treated with eight different approved antibiotics and five differen...

PURPOSE The aim of the study was to characterize clinical and environmental Staphylococcus pettenkoferi isolates with regard to genomic diversity and antibiotic susceptibility pattern. Repetitive-sequence-based PCR and core genome phylogenetic analysis of whole-genome sequencing (WGS) data verified the presence of distinct clades comprising closely related S. pettenkoferi isolates from differen...

Blood cultures are still considered to be the ‘gold standard’ for the detection of microbial pathogens related to bacteraemia and sepsis despite newer molecular techniques (4, 5). This method allows for microbial identification and susceptibility testing to be performed which is a critical component to managing sepsis, however the lack of rapid results and decreased sensitivity for fastidious p...

Gut microbiomes play crucial roles in animal health, and shifts in the gut microbial community structure can have detrimental impacts on hosts. Studies with vertebrate models and human subjects suggest that antibiotic treatments greatly perturb the native gut community, thereby facilitating proliferation of pathogens. In fact, persistent infections following antibiotic treatment are a major med...

Background: Rapid development of microbial resistance is an emerging health care issue of developing countries. In this study we evaluated the susceptibility pattern of bacterial pathogens causing catheters associated urinary tract infection (CAUTI) against commonly prescribed antibiotics alone and in combination with ascorbic acid in institutional settings. Method: The urine samples from 100 c...

There has been accelerating recognition that the field of microbial endocrinology provides a theoretical basis with which to propose and examine new biological mechanisms extending from susceptibility to infectious disease to food preferences. This is not surprising given the recognition that the microbiome plays a leading, if not central role, in the determination of health and pathogenesis of...

Emerging evidence indicates that processes during postnatal development might significantly influence the establishment of mucosal host-microbial homeostasis. Developmental and adaptive immunological processes but also environmental and microbial exposure early after birth might thus affect disease susceptibility and health during adult life. The present review aims at summarizing the current u...

Background and Objectives: Urinary tract infections (UTI) are one of the most common infectious diseases with different microbial agent and antimicrobial resistant pattern in hospitalized patients and outpatients. In order to assess the adequacy of therapy, knowledge of prevalence and resistance pattern of the bacteria is necessary. The main aim of this study was to evaluate the prevalence and ...

PROBLEM The increasing allergy prevalence in affluent countries may be caused by reduced microbial stimulation, resulting in an abnormal post-natal immune maturation. Most studies investigating the underlying mechanisms have focused on post-natal microbial exposure. Also, the maternal microbial environment during pregnancy may program the immune development of the child, however. METHOD OF ST...