We present unique molding/bonding processes to fabricate microstructured Ca-alginate hydrogel plates. We employed propylene glycol alginate (PGA), an ester derivative of alginate, which suppresses the shrinkage of sodium alginate (NaA) during the gelation process, and prepared microstructured hydrogel plates via molding. Also, a bonding procedure utilizing polycation coating is presented to obt...

We developed an inkjet-based DNA injector for microchip electrophoresis system based on a straight microchannel. The inkjet-based DNA injector enables us to precisely control injection volume of DNA and to use a simple straight microchannel for chip electrophoresis, whereas we need cross channel injector or T injector as well as complicated voltage programming for conventional chip electrophore...

Optimal formation of neuronal networks and synapses are essential for accomplishing higher brain functions. Extracellular molecules and nano-structures are considered to play important roles for in vitro studies of neuronal patterns. By using microcontact printing (μCP) and microchannel techniques, we found that neurons extended their neurites on μCP-defined biochemical patterns, whereas axons ...

This paper reports a new approach for constructing blood vessel-like tissues using microfluidic devices made of calcium-containing agarose hydrogel. Sodium alginate (NaA) solutions with different cell types at high densities were introduced stepwise into the hydrogel microchannel, to deposit cell-containing multiple Ca-alginate hydrogel layers on the channel surface with the help of Ca 2+ ions ...

Microchannels located at the cement–rock interface can form potential pathways for formation fluid leakage in oil and gas wells. The effects of geometric shape, quantity, inclination angle microchannels on flow through cemented rock samples were explored. Finite element 3D models established based modified micro-CT images obtained from physical samples. volume rate different sections was extrac...

changes of hydrodynamic parameters in microchannel branches affect the suspended biological samples in blood. to prevent denaturation and hemolysis, we have numerically investigated the effect of divergence angle on shear rate and velocity at branch entrance (discharge rate), under electroosmotic flow. in such flow, hydrodynamic properties are also affected by zeta potential at the microchannel...

In this paper, a dual-core microchannel-based fiber sensor is studied by using finite element method in the visible and near-infrared bands. Plasmonic material gold (Au) deposited microchannel to generate surface plasmon resonance (SPR) effect, so that can detect change RI of its surrounding analyte. Simulation results show maximum wavelength sensitivity resolution are 33600 nm/RIU 2.97 × 10−6R...

This work explains the simulation-based study to understand thermohydraulic characteristics (thermal resistance and pumping power) of a MEMS heat sink using serpentine microchannels employed for thermal management concentrated photovoltaic cells; planar dimensions both are 1 cm by cm. In this study, water is coolant constructed in silicon. Over Reynolds number varying from 50 1000 concentration...

Flows in a microfluidic environment differ their flow parameter changes compared to macro flows and should be handled carefully. Recently innovations have been drawn into much consideration biomedical, chemical synthesis, cooling industries. There exists need for rate sensor measuring tiny fluid developing Lab-on-chip products, Organ-on-chip, other products biological, chemical, analysis. Worki...

A microfluidic device is fabricated to characterize the streaming electrokinetic potential on the surface of charged electrospun nanofibers. The electrodes are made of evaporating with Ti and Au on an insulator, Pyrex® wafer, and are covered by a PDMS microchannel to form a microfluidic channel. The cationic or anionic charges of the electrospun charged nanofibers on the electrodes are interact...