Methods A new series of Nheterocyclic compounds has been derived from benzimidazole and pyrimidine nuclei optimized with the Discovery studio 3.0 software to investigate the interactions between the target compounds and the amino acid residues of Escherichia coli PDF Ni (PDB: ID 1G2A), and then synthesized. Further, all compounds were examined for their antibacterial activities against Gram-pos...

In this study, the synthesis of dimeric disulfide-Schiff bases was carried out using two methods. The structures obtained Schiff were elucidated by various spectroscopic methods as well elemental analysis. base derivative compounds (3a-6) screened for in vitro antibacterial activity against multidrug-resistant microorganisms microdilution method. All tested showed varying inhibition zones patho...

Endpoint determinations of endotoxin by the Limulus amoebocyte lysate assay have been facilitated by use of a microdilution procedure.

Broth microdilution susceptibility tests of Candida species have now been standardized by the National Committee for Clinical Laboratory Standards (NCCLS). An eight-laboratory collaborative study was carried out in order to document reproducibility of tests of Candida parapsilosis ATCC 22019 and Candida krusei ATCC 6258 by the NCCLS method. Replicate broth microdilution tests were used to defin...

results the sequence analysis of the isolate confirmed as c. glabrata and deposited on ncbi genbank under the accession number no. kt763084-kt763123. the geometric mean mics against all the tested strains were as follows, in increasing order: casp (0.17 g/ml), vcz (0.67 g/ml), amb (1.1 g/ml), itz (1.82 g/ml), ktz (1.85 g/ml), and fcz (6.7 g/ml). the resistance rates of the isolates to casp, fcz...