cystoid macular edema (cme) is a painless disease with different etiologies, which manifests as multiple cyst like (cystoid) spaces in the macula. cme is a common cause of vision loss following cataract surgery. some risk factors for post-cataract surgery cme include intraoperative complications specially incarceration of vitreous in the surgical wound, history of diabetes, uveitis and postoper...

PURPOSE To compare the results of combined and consecutive surgeries to treat proliferative diabetic retinopathy and cataract. METHODS Retrospective comparative study. Forty-one patients with proliferative diabetic retinopathy (PDR) were enrolled. Twenty-nine eyes for the combined surgery group and twelve eyes for the sequential group were included. All surgeries were performed by one surgeon...

PURPOSE Pharmacologic vitreolysis is a promising new therapy to improve vitreoretinal surgery and, ultimately, prevent disease by mitigating the contribution of vitreous to retinopathy. The mechanism of action of the agents being developed for pharmacologic vitreolysis remains unclear. The experiments in this thesis test the hypothesis that pharmacologic vitreolysis agents break down vitreous m...

PURPOSE To determine the intravitreal levels of vascular endothelial growth factor (VEGF) in eyes with anterior hyaloidal fibrovascular proliferation (AHFVP). METHODS Three eyes of three patients who underwent vitrectomy for proliferative diabetic retinopathy (PDR) and subsequently developed an AHFVP (AHFVP group) were studied. We measured the level of VEGF in vitreous samples collected at th...

BACKGROUND Maple syrup urine disease (MSUD) is a rare metabolic disorder, affecting the metabolism of branched chain amino-acids (Valine, Leukine, Isoleukine). We present a rare case of rhegmatogenous retinal detachment (RRD) in a MSUD patient. CASE PRESENTATION We performed amino acid analysis of aqueous humour, vitreous and serum samples obtained during surgery from a 24 year old female MSU...

PURPOSE This study aimed to report the use of intravitreal bevacizumab as an adjunctive treatment in two cases of advanced Eales' disease with vitreous haemorrhage and tractional retinal detachment, prior to vitreoretinal surgery. METHOD In two patients presenting with vitreous haemorrhage, retinal neovascularisation and localised tractional retinal detachment, 1.25 mg of intravitreal bevaciz...

Adequate visualization and identification of the posterior hyaloid, epiretinal membranes and the internal limiting membrane are of paramount importance in modern vitreoretinal surgery. "Chromovitrectomy" is a term used for describing the vital dyes use in order to stain these transparent tissues and facilitate their manipulation during vitreous surgery. This article reviews the indications, app...