This is a case report of concurrent of blastomycosis and pseudomycetoma in a 3 year-old Persian cat from Bangkok, Thailand. Histopathology from antemortem and postmortem samples revealed blastomycosis and dermatophyte pseudomycetoma. The PCR analysis of the formalin-embedded tissue of antemortem sample confirmed that blastomycosis was caused by Blastomyces dermatitidis. Dermatophyte infection w...

Antifungal activity of ethanolic leaf extract of Limonia acidissima was studied against three common dermatophytic fungai like Trichophyton mentagrophytes, Microsporum canis and Epidermophyton floccosum by disc diffusion method and zone of inhibition was determined. Ketoconazle was used as reference control. The ethanolic leaf extract of Limonia acidissima exhibited antifungal activity against ...

Comparative efficacy of miconazole nitrate, graphite, Thuja and Chrysorobin ointments was assessed against three keratinophillic fungi, viz., Trichophyton terrestris, Chrysosporium tropicum and Microsporum gypseum. All the test fungi were sensitive to the anti microbials tested in the present study. Miconazole nitrate, showed the maximum activity followed by Graphite, and Thuja, whereas the min...

A síntese, a caracterização espectroscópica e os resultados biológicos de novas séries de 2-(4-piridil)-1,2,3,4-tetrahidroquinolinas e seus precursores, -N-aril-N-[1-(4-piridil)but-3-enil] aminas, são descritos. Foi encontrado que ambos, precursores substituídos g-piridil e os produtos finais, as tetrahidroquinolinas, demonstraram excelentes atividades antifúngicas contra Aspergillus fumigatus,...

Dermatophytosis (tinea) infections are fungal infections caused by dermatophytes a group of fungi that invade and grow in dead keratin. Several species commonly invade human keratin and these belong to the Epidermophyton, Microsporum and Trichophyton genera. They tend to grow outwards on skin, producing a ringlike pattern hence the term 'ringworm'. They are very common and affect different part...

Cells of Candida parapsilosis were extracted sequentially with different organic solvents. The sodium carbonate wash of the methanol extract showed carcinogenic activity in mice as demonstrated by the appearance of 6 sarcomas at the site of injection in a group of 16 animals. Suggestive carcinogenic activity in the appearance of subcutaneous sarcomas and increased frequency of leukemias and pul...

Dermatophytoses are superficial infections of keratinized tissues like hair, skin and nail, caused by a specialized group of fungi closely related antigenically, physiologically and morphologically, known as dermatophytes or ringworm fungi (Rabell and Taplin, 1974). The etiologic agents of the dermatophytoses are classified in three anamorphic (asexual or imperfect) genera, Epidermophyton, Micr...

Antifungal activities of clove essential oil and its volatile vapour against dermatophytic fungi including Candida albicans, Epidermophyton floccosum. Microsporum audouinii, Trichophyton mentagrophytes, and Trichophyton rubrum were investigated. Both clove essential oil and its volatile vapour strongly inhibit spore germination and mycelial growth of the dermatophytic fungi tested. The volatile...

Hybridoma cells produced by fusing myeloma cells with spleen cells from mice immunized with a soluble antigen of Microsporum canis yielded 30 antibody-producing clones. Six of these clones, propagated as ascites tumors in mice, showed two different types of monoclonal antibodies. The type 1 monoclonal antibody reacted with 17 heterologous and 10 homologous dermatophyte antigens. Type 2 monoclon...