background: migraine consisting of migraine with aura (ma) and migraine without aura (mo) is a painful neurovascular disorder affecting approximately 16% of the general population. a combination of genetic and environmental factors is involved in the pathogenesis of migraine. the mthfr enzyme is involved in homocysteine (hcy) metabolism and it has been reported that 1298 a to c and 677 c to t m...

BACKGROUND Neurocysticercosis is a major cause of neurological symptoms in developing countries. We report a case of cerebral neurocysticercosis presenting as episodic migraine without aura, with clinico-radiological correlations and discuss the possible causal influence of neurocysticercosis on the pathomechanisms of migraine. CASE PRESENTATION We report a 24 year-old male consulting for a o...

OBJECTIVES The aim of this study was to assess the prevalence of right-to-left (R to L) shunt in patients with visual aura and evaluate the effect of shunt closure on resolution of aura. BACKGROUND Right-to-left shunting is associated with migraine headache (MH) with aura. Some patients present with visual aura without headaches. It is unclear whether visual aura without headache is a form of...

BACKGROUND Headache is one of the most disturbing symptoms with common neurological signs. Variations in optic nerve perfusion quality or retinal microcirculation may end up in ganglion cell damage in patients with migraine. METHODS Sixty patients diagnosed with migraine and thirty normal individuals were evaluated in groups including migraine with aura, migraine without aura and controls. Re...

BACKGROUND Synesthesia is, as visual migraine aura, a common and fascinating perceptual phenomenon. Here we present a unique case with synesthesias exclusively during visual migraine auras. CASE PRESENTATION A 40-year-old woman with a cyclic mood disorder had suffered from migraine with visual aura for several years. On several occasions she had experienced "mixing of senses" during the aura ...

Neurologic symptoms are a prominent and often disturbing component of the migraine syndrome in many patients. Collectively termed "aura," migraine-related neurologic symptoms include visual, sensory, language, and motor disturbance. They occur in about one quarter of migraine patients, are classically transient, and are thought to occur as the result of cortical phenomena. Recently, motor sympt...

Migraine is a serious health problem which impair quality of life. It is the second most common primary headache that affects approximately more than %10 people in general population. Migraine pathophysiology is still unclear. Increasing results of studies suggest to migraine pathophysiology is related with primary neuronal mechanisms. Migraine pain starts in which region of brain and what brai...

Recent advances in genetics have shown the importance of the genetic component on migraine. Studies on twins also point out to the importance of genetic migraine. On the other hand, epidemiological data identified environmental factors that are important in the genesis of migraine. Studies on familial hemiplegic migraine with or without aura will certainly bring new information and help underst...

BACKGROUND AND PURPOSE The aura phase of migraine is associated with focal blood flow changes, but it has been largely unknown whether these changes are correlated to changes in the cerebral metabolism. METHODS Eight patients required carotid angiography for evaluation of transient neurological attacks. Cerebral blood flow (CBF) results, angiography, and clinical observations subsequently sug...

Migraine is a common disabling disorder characterized by recurrent headaches and at times non-painful episodic phenomena associated with a variety of neurological manifestations. It ranks among the top 20 causes of disability worldwide [1]. It therefore has a substantial impact on individuals as well as on society. A community based study on headaches in Malaysia showed the prevalence of migrai...