background: the present study assesses independent predictors of clinically important traumatic brain injury (citbi) in order to design a prognostic rule for identification of high risk children with mild head injury. materials and methods: in a retrospective cross-sectional study, 3,199 children with mild traumatic brain injury (tbi) brought to emergency ward of three hospitals in tehran, iran...

A review of the top-cited articles in a scientific discipline can identify areas of research that are well established and those in need of further development, and may, as a result, inform and direct future research efforts. Our objective was to identify and characterize the top-cited articles in traumatic brain injury (TBI). We used publically available software to identify the 50 TBI article...

Methods Twenty-four patients and three controls (21 men, 6 women, mean age 33.4 years, age range 19-54) were recruited and scanned on 3T or 7T GE Excite scanners. Five TBI patients scanned at 3T received a repeat scan 1 to 12 months after the first scan, for a total of 23 scans at 3T and 9 scans at 7T. Sixteen of the patients had mild TBI (Glasgow Coma Scale (GCS) 13-15), three moderate TBI (GC...

OBJECTIVE Because reduction of the microtubule-associated protein Tau has beneficial effects in mouse models of Alzheimer's disease and epilepsy, we wanted to determine whether this strategy can also improve the outcome of mild traumatic brain injury (TBI). METHODS We adapted a mild frontal impact model of TBI for wildtype C57Bl/6J mice and characterized the behavioral deficits it causes in t...

Traumatic brain injury (TBI) is suggested to be a significant risk factor for dementia. However, little research has been conducted into long-term neuropsychological outcomes after head trauma. Participants from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing (AIBL) who had recovered after sustaining a mild TBI involving loss of consciousness more than 5 years previously were c...

Traumatic brain injuries (TBI) are a major public health problem with enormous costs in terms of health care dollars, lost productivity, and reduced quality of life. Alcohol is bidirectionally linked to TBI as many TBI patients are intoxicated at the time of their injury and we recently reported that, in accordance with human epidemiological data, animals injured during juvenile development sel...

BACKGROUND Approximately 1 million individuals experience a mild traumatic brain injury (TBI) and cost the United States nearly $17 billion each year. Many trauma survivors with mild TBI have debilitating and long-term physical, emotional, and cognitive impairments that are unrecognized at trauma centers. Early intervention studies are needed to address these impairments, especially cognitive d...

Traumatic brain injury (TBI) is defined as dysfunction or other evidence of pathology caused by external physical force. More than 69 million new cases TBI are registered worldwide each year, 80% them - mild TBI. Based on the mechanism induced trauma, we can separate its pathophysiology into primary and secondary injuries. Many literature sources have confirmed that mechanically initiates ionic...

Summary A 3‐year‐old Thoroughbred mare found recumbent in the field was referred for further assessment with suspicion of a skull fracture. Neurological examination identified compulsive tight circling to left, and hypermetria all four limbs. The obtunded, mild head tilt right, absent menace response right eye decreased facial sensation on right. Standing computed tomographic revealed subtle de...

BACKGROUND Traumatic brain injury (TBI) has been associated with an acute stress response mediated by the sympathoadrenomedullary axis, which can be assessed by measuring blood glucose level. METHODS This prospective observational study was conducted for a year in 2007 among 294 patients who had been treated for TBI in Hospital Kuala Lumpur. Patients fulfilling the set criteria were recruited...