this study was designed to develop a modified tbi weight drop model for induction of focal mild cerebral injury. a stereotaxic coupled weight drop device was designed. principle arm of device carries up to 500g weights which their force was conveyed to animal skull through a thin nail like metal tip. to determine the optimal configuration of the device to induce mild tbi, six different trials w...

background several lines of evidence suggest that early sensory stimulation and regular family visiting programs are potential nursing interventions to improve the outcomes of head injured comatose patients. however, little is known about the impacts of family involvement in providing sensory stimulation. objectives to determine the effects of a sensory stimulation program conducted by nurses a...

objective(s): neuroprotective effects of female gonadal steroids are mediated through several pathways involving multiple peptides and receptors after traumatic brain injury (tbi). two of these peptides are including the regulatory peptides neuromedin u (nmu) and neuromedin s (nms), and their common receptor neuromedin u2 receptor (nmur2). this study investigates the effects of physiological do...

introduction: brain injury is an important cause of morbidity and mortality worldwide and so far, there has been no absolute treatment for the damaged brain tissue. using human stem cells with self-assembling scaffolds can be a promising method for treatment of traumatic brain injury. materials and methods: human meningioma stem cells were isolated, cultured and then expanded into in vitro cond...

introduction: timely diagnosis and treatment of post traumatic, elevated intracranial pressure (eicp), could reduce morbidity and mortality, as well as improve patients’ outcome. this study is trying to evaluate the diagnostic accuracy of sonographic optic nerve sheath diameter (onsd) in detection of eicp. methods: sonographic onsd of patients with head trauma or cerebrovascular accident suspic...

MAIN RESULTS After one year, prevalence of psychiatric illness significantly increased in people with moderate to severe and mild traumatic brain injury, compared with controls (moderate to severe: 49%; mild: 34%; control: 18%; see table 1, http://www.ebmentalhealth.com/ supplemental). People with prior psychiatric illness are more likely to suffer from a psychiatric illness after traumatic bra...

Citation: Thibeault CM, Thorpe S, O’Brien MJ, Canac N, Ranjbaran M, Patanam I, Sarraf A, LeVangie J, Scalzo F, Wilk SJ, Diaz-Arrastia R and Hamilton RB (2018) A CrossSectional Study on Cerebral Hemodynamics After Mild Traumatic Brain Injury in a Pediatric Population. Front. Neurol. 9:200. doi: 10.3389/fneur.2018.00200 a cross-sectional study on cerebral hemodynamics after Mild Traumatic Brain i...