asthma is the most common chronic disease of childhood. exposure to allergens plays an important role in asthma. recently, cockroach has attracted attentions as an important allergen. this study was performed to evaluate cockroach allergy in iranian children with asthma. one hundred children with definite diagnosis of asthma were selected. after obtaining primary information, the severity of th...

Methods We realized a 2 years ambispective study for assessment safety and efficacy of subcutaneous immunotherapy with a dust mite vaccine with the adjuvant L-tyrosine. We reviewed the data of 292 patients with allergic rhinitis and/or asthma. They are sensitized to Dermatophagoides pteronyssinus or Dermatophagoides farinae and or Blomia tropicallis. A data base was constructed to allow complet...

We compared a newer serum specific IgE (SSIgE) test with skin prick testing (SPT) in the diagnosis of allergy in Malaysia. Ninety newly diagnosed allergic patients were enrolled for both tests. Using SPT as a clinical gold standard, the sensitivity, specificity, positive, and negative predictive values (PPV, NPV) were calculated for SSIgE for each of the common allergens tested. The highest pos...

A double-blind clinical trial of hyposensitization with aqueous extracts of Dermatophagoides pteronyssinus (the house-dust mite) and human skin scales showed a substantial improvement in symptoms in 11 asthmatics allergic to house dust treated with the D. pteronyssinus extract and a reduction in their need for other therapy. Five patients were well for a year but six relapsed. These results con...

Objective Allergic rhinitis (AR) is a major chronic respiratory disease due to its prevalence, impact on quality of life (QL), economic burden, link with asthma. During the last years, many countries have experienced an increase in the prevalence of respiratory allergy. A significant contribution in development of AR, in addition to house dust mite, cockroaches, dogs, cats, pollen and trees, se...

Dr Bernstein is professor of clinical medicine in the department of internal medicine, division of immunology/allergy, at the University of Cincinnati College of Medicine. jonatHan a. BERnstEIn, MD university of Cincinnati E xposure to environmental allergens is associated with the development of allergic rhinitis and asthma; appropriate interventions can reduce indoor allergen exposure and imp...