نتایج جستجو برای: mitsunobu
تعداد نتایج: 201 فیلتر نتایج به سال:
UK-2A, B, C and D (UK-2 compounds) were isolated from Streptomyces sp. 517-02, and are similar to antimycin A3 (AA) in their structure and inhibitory activities towards electron transport at complex III in mitochondria1-3). However, the benzyl group at the C2 position in UK-2A (main component of UK-2 compounds) has never been found in known antimycins and a methyl group is lacking at the C8 pos...
We report the design and synthesis of 2'-fluoro cyclohexenyl nucleic acid (F-CeNA) pyrimidine phosphoramidites and the synthesis and biophysical, structural, and biological evaluation of modified oligonucleotides. The synthesis of the nucleoside phosphoramidites was accomplished in multigram quantities starting from commercially available methyl-D-mannose pyranoside. Installation of the fluorin...
INTRODUCTION Enzymatic polymerization has been extensively developed over the past two decades.1–7 In particular, horseradish peroxidase (HRP) has been used for enzymatic oxidative polymerization of phenolic compounds. Dordick and co-workers8,9 reported HRP-catalyzed polymerization of arbutin, a glucose-bearing phenol derivative. Water-soluble polyarbutins with molecular weight (Mn) in the rang...
Strigolactones are signaling compounds in plants of increasing importance. In this paper the focus is on their activity as germinating agents for seeds of parasitic weeds. The syntheses of aromatic A-ring analogues of the germination stimulant orobanchol have been described. Starting substrate is the ABC unit of the stimulant GR24. Oxidation at the C-4 position gives a 4-oxo derivative which on...
Mitsunobu Matsubara, MD, Department of Nephrology, Sendai Shakaihoken Hospital, 3-16-1 Tsutsumimachi, Aoba-ku, Sendai 981 (Japan) Table 1. Changes in clinical data during 3 weeks of camostat mesilate administration Dear Sir, Camostat mesilate is a protease inhibitor developed for oral use. Recently we found its efficacy on proteinuria in patients with various glomerulonephritides including IgA ...
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