Protein crystals obtained in initial screens typically require optimization before they are of X-ray diffraction quality. Seeding is one such optimization method. In classical seeding experiments, the seed crystals are put into new, albeit similar, conditions. The past decade has seen the emergence of an alternative seeding strategy: microseed matrix screening (MMS). In this strategy, the seed ...

Mobile messaging is evolving beyond SMS text messaging with the introduction of MMS (Multimedia Messaging Service). In the past, such a scheme is used to peer-to-peer communication. Messages are generally displayed on handset with a limited-sized screen. However, such a visualizing process is not suitable to broadcast real-time SMS/MMS messages to a crowd of people in public. To facilitate the ...

Mobile devices are becoming more important in daily lives for information gathering, personal management, appointment management and many others. They also have gained increasing relevance in education field, for example Short Messaging Service (SMS)-based examination results system. In this particular system, though we could gain many benefits out of it, limitations do still exist. Firstly, SM...

BACKGROUND The failure of Mycobacterium bovis Bacille Calmette-Guérin to impart satisfactory protection against adult pulmonary tuberculosis has necessitated the development of more effective TB vaccines. The assumption that the vaccine strain should be antigenically as similar as possible to the disease causing pathogen has led to the evaluation of M.tuberculosis mutants as candidate tuberculo...

PURPOSE Even though the importance of micrometastases (MMS) and isolated tumor cells (ITC) has been brought up by many physicians, its impact on the prognosis in stage II colorectal cancer is uncertain. In this research, we tried to investigate the clinical features of MMS and ITC and to prove any correlation with prognosis. METHODS The research pool was 124 colorectal cancer patients who und...

The hull designs of the Peruvian fishing fleet lack hydrodynamic studies, which is why, in present work, a study resistance to advance classical model type mentioned, called "MMS", carried out. An experimental numerical correlation out with this validate proposed methodology.
 methodology uses CFD using Ansys-Fluent software, considering turbulent behaviour for multiphase fluid (water-air)...

In response to replication stress, a phospho-signaling cascade is activated and required for coordination of DNA repair and replication of damaged templates (intra-S-phase checkpoint) . How phospho-signaling coordinates the DNA replication stress response is largely unknown. We employed state-of-the-art liquid chromatography tandem-mass spectrometry (LC-MS/MS) approaches to generate high-covera...

Escherichia coli translation initiation factor 2 (IF2) performs the unexpected function of promoting transition from recombination to replication during bacteriophage Mu transposition in vitro, leading to initiation by replication restart proteins. This function has suggested a role of IF2 in engaging cellular restart mechanisms and regulating the maintenance of genome integrity. To examine the...

BACKGROUND Basal-cell carcinoma (BCC) is the most common form of skin cancer and its incidence is still rising worldwide. Surgery is the most frequently used treatment for BCC, but large randomised controlled trials with 5-year follow-up to compare treatment modalities are rare. We did a prospective randomised controlled trial to compare the effectiveness of surgical excision with Mohs' microgr...

Introduction: Until now micrometeorites have been extracted from limited periods of geological time (up to ~185-Myr-old) providing only a fragmented record of MM flux changes over geological time [1]. Because of preservation problems, we did not think MMs could be recovered from salt deposits (such as halite). Here we report that not only can MMs be found in, and successfully extracted from, ha...