نتایج جستجو برای: moderate dose
تعداد نتایج: 481276 فیلتر نتایج به سال:
Objectives: To examine the relationship of food insecurity with sexual intercourse, multiple partners and non-condom use. Methods: Data on (hunger) behaviors from 205,296 adolescents 53 countries. Associations were analyzed using meta-analysis. Results: Overall, 16.0% ever had intercourse prevalence moderate severe was 44.9% 6.2%, respectively. Moderate associated higher odds for intercourse. A...
BACKGROUND Inhaled glucosteroids and oral theophylline are widely used to treat asthma. We compared the benefits of adding theophylline to inhaled glucosteroid with those of doubling the dose of inhaled glucosteroid in patients with persistent symptoms despite the use of inhaled glucosteroid. METHODS In a double-blind, placebo-controlled trial, we randomly assigned 62 patients to receive eith...
background: in vivo dosimetry is a method for estimation of overall error in the delivered dose to the patients at the end of radiotherapy process. in this research, two methods for target dose calculation were evaluated on midline and central axis of photon beams in in vivo dosimetry of thorax fields. materials and methods: entrance and exit doses for anterior and lateral fields of thorax were...
Fixed-dose combinations (FDCs) are one of the options for improving blood pressure (BP) goal attainment. We enrolled 141 patients and evaluated the efficacy and safety between a fixed dose of olmesartan/amlodipine (OA) and a double dose of amlodipine (DA) for treating mild to moderate hypertension after amlodipine monotherapy failure. After at least 2 weeks of monotherapy failure, the patients ...
BACKGROUND Radioiodine (131 I) is effective treatment for hyperthyroidism in cats, but optimal dose to restore euthyroidism without inducing hypothyroidism is unclear. Treatment-induced hypothyroidism can lead to azotemia and reduced duration of survival. OBJECTIVE To compare efficacy and short-term outcomes of low-dose 131 I versus higher, standard-dose 131 I as treatment for hyperthyroidism...
Background: The role and proper dose of pralidoxime in the treatment of Organophosphorus (OP) compounds poisoning is an unresolved issue .This study was designed to compare the regimen recommended by the World Health Organization (WHO) with the commonly used standard regimen of pralidoxime. Methods: This was a randomized open labeled prospective study on OP poisoned patients admitted to JSS Hos...
OBJECTIVES We examined overall and incremental effectiveness of 2-dose varicella vaccination in preventing community transmission of varicella among children aged 4 to 18 years in 2 active surveillance sites. One-dose varicella vaccine effectiveness (VE) was examined in those aged 1 to 18 years. METHODS From May 2009 through June 2011, varicella cases identified during active surveillance in ...
BACKGROUND Guanfacine extended-release (GXR) is an orally administered, non-stimulant treatment for children and adolescents with attention-deficit/hyperactivity disorder (ADHD) and is primarily metabolized by the 3A4 isozyme of cytochrome P450 (CYP3A4). The results of clinical pharmacokinetic (PK) studies indicate that guanfacine is sensitive to drug-drug interactions (DDIs) perpetrated by str...
PURPOSE Pazopanib is a potent, multitargeted receptor tyrosine kinase inhibitor; however, there is limited information regarding the effects of liver function on pazopanib metabolism and pharmacokinetics. The objective of this study was to establish the maximum-tolerated dose (MTD) and pharmacokinetic profile of pazopanib in patients with varying degrees of hepatic dysfunction. EXPERIMENTAL D...
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