BACKGROUND L-tryptophan is an important ingredient in medicines, especially in neuromedicines such as antidepressants. Many commercial processes employ various microorganisms with high tryptophan synthase activity to produce L-tryptophan from indole and L-serine, but these processes are very costly due to the costs of precursors, especially L-serine. OBJECTIVES For this reason, we studied the...

BACKGROUND L-tryptophan is used widespread in the pharmaceutical industry. The majority of L-Trp production depends on microbial processes that produce L-tryptophan from indole and L-serine. These processes are very costly due to the costs of precursors, especially L-serine. Use of inexpensive substitutions as the L-serine source of L-tryptophan production enables us to reach a cost-effective p...

Distillery sludge is a major source of aquatic pollution, but little known about their microbial community and association with the organic metal pollutants. Sugarcane molasses-based distillery an important industry in India, although waste usually treated prior to disposal, treatment often inadequate. The adverse effects pollutants sugarcane on biodiversity abundance disposal site have not bee...

Erratum: “Radionuclides in Fracking Wastewater: Managing a Toxic Blend” The Focus article “Radionuclides in Fracking Wastewater: Managing a Toxic Blend” [Environ Health Perspect 122:A50–A55 (2014); http://dx.doi.org/10.1289/ehp.122-A50] incorrectly stated that Pennsylvania requires pit liners for temporary impoundments and disposal to have a minimum thickness of 30 mm. The correct minimum thick...