The Laschamp Geomagnetic Excursion (ca. 41 ka) and a related increase of cosmogenic nuclides provides a global tie point among sedimentary and ice core records. In the Wilson Creek Formation, Mono Lake, California, the Laschamp Excursion has not been recognized although the so-called Mono Lake excursion was found in the section with an estimated age of about 28 14C ka. However, our reevaluation...

The sirtuin gene family comprises an evolutionarily ancient set of NAD+ dependent protein deacetylase and mono-ADP ribosyltransferase enzymes. Found in all domains of life, sirtuins regulate a diverse array of biological processes, including DNA repair, gene silencing, apoptosis and metabolism. Studies in multiple model organisms have indicated that sirtuins may also function to extend lifespan...

The subcellular distribution, size, and activation state of protein kinase C (PKC) were studied after short term exposure of rabbit platelets to a saturating dose of 12-O-tetradecanoylphorbol 13-acetate (TPA). Cytosolic and Nonidet P-40-solubilized particulate extracts prepared from TPA-treated platelets were subjected to analytical column chromatography on Mono Q, hydroxylapatite, and Superose...

The Mono Model Checker (mmc) is a software model checker for cil bytecode programs. mmc has been developed on the Mono platform. mmc is able to detect deadlocks and assertion violations in cil programs. The design of mmc is inspired by the Java PathFinder (jpf), a model checker for Java programs. The performance of mmc is comparable to jpf. This paper introduces mmc and presents its main archit...

The paper reviews some recent progress on adaptive signal decomposition into mono-components that are defined to be the signals of non-negative analytic phase derivatives.

The use of glass capillaries (the so-called mono-capillaries) as incident beam optical module for X-ray micro-diffraction is evaluated. These mono-capillaries show a gain in intensity with a typical factor of three over traditional pinhole collimators. Procedures to improve the particle statistics of the measurement are discussed. Examples are shown on phase identification and preferred orienta...