Radiosensitization using gold nanoparticles (AuNPs) has been shown to vary widely with cell line, irradiation energy, AuNP size, concentration and intracellular localization. We developed a Monte Carlo-based AuNP radiosensitization predictive model (ARP), which takes into account the detailed energy deposition at the nano-scale. This model was compared to experimental cell survival and macrosco...

Background: Prostate cancer is known as one of the most prevalent health disorders in the male population globally. The aim of the current study was to evaluate the effects of separate and concomitant use of MK-2206 and salinomycin on prostate cancer cell line.  Methods: The antitumor potential of separate and concomitant use of MK-2206 and salinomycin was evaluated in a panel of prostate ca...

As the world advances, statisticians/mathematicians are being involved into more and more complex surveys for the development of society and human beings. Consequently, these complex survey data requires complicated and high-dimensional models for final analysis. We need sophisticated and efficient statistical/mathematical tools for estimation and prediction of these models. Frequently, we simu...

background: prostate cancer is the most common malignancy among the male population in the united states and the 3rd most common non-skin cancer among men in iran. its prevalence has shown a rising trend in recent decades. the aim of this study was to report the epidemiological features of prostate cancer in patients referred for prostate biopsy in the south of iran and to evaluate the accuracy...

background: prostate specific antigen (psa) is a protein currently used in vconjunction with the digital rectal examination to detect and guide management of prostate cancer. there are several causes of increase in serum psa including urological manipulations, medications, prostatic diseases, prostate cancer, prostate inflammation or infection, etc. some studies had reported cystoscopy to cause...

conclusions results showed that whereas knowledge by itself cannot guarantee men’s participation in prostate cancer screenings, perceived barriers can play an important role in discouraging men from cancer screening participation. therefore, designing programs to address these barriers is very important. results the most common barriers to screening for prostate cancer were a lack of knowledge ...

conclusions our study showed that microrelin is as effective as diphereline in reducing psa and testosterone and can be recommended to initiate medical castration in patients with pc. results each group contained 40 patients. in group a, psa was reduced from 75.78 ± 72.43 ng/ml to 1.93 ± 1.40 ng/ml after 6 months and testosterone was reduced from 3.50 ± 1.12 nmol/l to 0.81 ± 0.05 nmol/l. there ...