We propose a shape analysis system based upon the description of landmarks with measurement covariance, which extends statistical linear modelling processes to ‘pseudo landmarks’ for scientific studies. We discuss the properties of our approach and how measurement covariances can be considered characteristic of the local shape. Our formulation includes corrections for parameter bias, induced by...

Due to the very unique disposition of the articular surfaces associated with the talus, the bone and its constituent components (body and the head) are oriented in specialised spatial orientation. Thus, the force subjected to the talus in load bearing not only dictates the resultant shapes and dimensions of the articular surfaces acquired by the bone, stress on the talus also probably decides t...

BACKGROUND Determining the sex of deceased is easy when a complete skeleton is available for examination. On the whole, the bones are heavier, larger and markings of muscular attachments are more pronounced in the male than in the female. OBJECTIVE The purpose of this study was attempted to evolve an easily applied formula to enable the assessment of sex in an unknown clavicles and to know ab...

RATIONALE AND OBJECTIVES To investigate the relationships between brain and skull base growth in patients with neurofibromatosis 1 (NF1) compared with healthy control subjects using brain magnetic resonance imaging (MRI) for morphometric analysis. METHODS Evaluated patients included children who underwent T1- and T2-weighted or dual-echo proton density axial and T1-weighted sagittal brain MRI...

In 2 studies, a method of linear morphometry was applied to regulatory developmental neurotoxicity studies in the rat. The first study involved the development of the brain during postnatal days (PNDs) 7-63, and the second involved the effects of 8 mg/kg i.p. trimethyltin chloride (TMT) to rats at PND 8, with morphometry performed at PNDs 12 and 24. The results of the TMT linear morphometry wer...

BACKGROUND Measurement of corneal endothelial cell density is important both for clinical diagnosis as well as clinical studies. Since endothelial cell loss is considered irreversible in humans, even small changes in endothelial cell density are relevant. Therefore it is important to know whether different instruments for endothelial cell density measurements give the same results and can thus ...

The intrinsic viscoelastic properties of muscle are central to many theories of motor control. Much of the debate over these theories hinges on varying interpretations of these muscle properties. In the present study, we describe methods whereby a comprehensive musculoskeletal model can be used to make inferences about motor control strategies that would account for behavioral data. Muscle acti...

Magnetic resonance imaging has proved to be suitable and efficient for in vivo investigation of the early process of brain gyrification in fetuses and preterm newborns but the question remains as to whether cortical-related measurements derived from both cases are comparable or not. Indeed, the developmental folding trajectories drawn up from both populations have not been compared so far, neit...

An overview of computational procedures for examining neuroanatomical variability is presented. The review focuses on approaches that can be applied using the SPM software package, beginning by explaining briefly how statistical parametric mapping is usually applied to functional imaging data. The review then proceeds to discuss volumetry, with an emphasis on voxel-based morphometry, and the pr...

Synesthesia is a rare condition in which stimulation in one modality leads to a secondary experience in another sensory modality. Varying accounts attribute the condition to either neuroanatomical differences between the synesthetes and non-synesthetes or functional differences in how sensory brain regions interact. This study employed voxel-based morphometry to examine whether synesthetes who ...