BACKGROUND The purpose of the present study is to investigate the anesthetic effect of reduced doses of spinal bupivacaine with epidural top ups in comparison with those of spinal bupivacaine and to determine the adequate doses of drugs used during lower extremity surgeries. METHODS SIXTY ADULT PATIENTS WERE RANDOMIZED TO THREE DIFFERENT TECHNIQUE GROUPS: S group (10 mg of spinal bupivacaine)...

Local anesthetic efficacy of tramadol has been reported following intradermal application. Our aim was to investigate the effect of perineural tramadol as the sole analgesic in two pain models. Male Wistar rats (280-380 g; N = 5/group) were used in these experiments. A neurostimulation-guided sciatic nerve block was performed and 2% lidocaine or tramadol (1.25 and 5 mg) was perineurally injecte...

A patient had a prolonged block after continuous extradural analgesia in labour. The block was unilateral, but 60 min after a second block there was bilateral sensory and motor loss. The original unblocked side did not recover fully until more than 60 hr. The local anaesthetic agent was 18 ml of bupivacine 0.5% plain.

Apraxia caused by left hemispheric stroke typically impairs skilled sequential movements. After stroke, apraxic patients need to reacquire motor skills by motor learning. The current study assessed for the first time incidental motor sequence learning in apraxic patients. Forty-eight human subjects (henceforth called "patients") with left hemispheric stroke affecting the middle cerebral artery ...

PURPOSE To provide a review of local anesthetic (LA) agents and adjuncts, opioids and muscle relaxants, and their intraoperative effects and postoperative outcomes in intravenous regional anesthesia (IVRA). SOURCE A search for prospective, double-blind, randomized controlled trials evaluating LA agents, opioids and muscle relaxants as adjuvants for IVRA, was conducted (MEDLINE(®), Embase). In...

Background and Aims The aim of the study was to evaluate the effectiveness of epidural volume extension (EVE) technique in terms of sensory and motor block characteristics along with hemodynamic parameters as a part of combined spinal-epidural anesthesia (CSEA). Materials and Methods A total of 60 patients undergoing hip surgeries were assigned to one of the two groups containing 30 patients ...

the present study was designed to assess the efficacy of fentanyl and pancuronium combined with dilute lidocaine solution for axillary block. onehundred adult patients undergoing upper limb surgery were randomly allocated to receive either 0.6 ml/kg of 1 % lidocaine (6 mg/kg) or 0.6 mllkg of 0.5% lidocaine (3 mg/kg) with 1 µg/kg of fentanyl and 0.5 mg of pancuronium. the onset of sensory and mo...

conclusions when itbs was applied over the primary motor cortex, it significantly improved manual dexterity, but had no significant effect on the hand motor imagery ability in ms patients. results itbs group showed a reduction in the time required to complete the 9hpt (mean difference = -3.05, p = 0.002), and an increase in the number of blocks transferred in one minute in the bbt (mean differe...

conclusions the addition of 2.5-3 mcg sufentanil to 15 mg 0.05% bupivacaine maintained the patient’s hemodynamic stability similar to fentanyl. intrathecal sufentanil added to bupivacaine,when compared with fentanyl, may lead to prolonged duration of analgesia, facilitate the spread of the sensory block, increase mean spo2 levels, and reduce overall side effects. background the addition of intr...