Methylprednisolone (MP) is used to treat a variety of neurological disorders involving white matter injury, including multiple sclerosis, acute disseminated encephalomyelitis, and spinal cord injury (SCI). Although its mechanism of action has been attributed to antiinflammatory or antioxidant properties, we examined the possibility that MP may have direct neuroprotective activities. Neurons and...

PURPOSE This study determined the effects of chitosan (CTS) and water-soluble chitosan (WSC) microparticles (MPs) and nanoparticles (NPs) in rats with high-fat diet-induced obesity. METHODS THE RATS WERE RANDOMLY SEPARATED INTO EIGHT GROUPS: a normal diet group (the blank control), a high-fat emulsion group (the negative control), CTS and WSC control groups, CTS-MP and WSC-MP groups, and CTS-...

BACKGROUND The addition of myocardial perfusion (MP) imaging during dipyridamole real-time contrast echocardiography improves the sensitivity to detect coronary artery disease, but its prognostic value to predict hard cardiac events in large numbers of patients with known or suspected coronary artery disease remains unknown. METHODS AND RESULTS We studied 1252 patients with the use of dipyrid...

We introduce the class MP of languages L which can be solved in polynomial time with an oracle for one selected bit of the value f (y) of a #P function f on a selected argument y. This extends the much-studied language classes P and PP, which correspond to the power of the least and most signiicant bits, respectively. We show that MP is captured by the power of the middle bit; namely: a languag...

OBJECTIVES To assess the prevalence and associations of mesenteric panniculitis (MP) using multi-detector CT (MDCT). METHODS This retrospective study included 4758 consecutive patients who underwent abdomino-pelvic MDCT between January 2012 and December 2014 at Jordan University Hospital, Amman, Jordan. Radiological database was searched for MP diagnosis and patients with suspected MP were re...

IL-23 induces IL-17 production in activated CD4+ T cells and participates in host defense against many encapsulated bacteria. However, whether the IL-23/IL-17 axis contributes to a Mycoplasma pneumoniae (Mp)-induced lung inflammation (e.g., neutrophils) has not been addressed. Using an acute respiratory Mp infection murine model, we found significantly up-regulated lung IL-23p19 mRNA in the ear...

The intensity and spatial distribution of functional activation in the left precentral and postcentral gyri during actual motor performance (MP) and mental representation [motor imagery (MI)] of self-paced finger-to-thumb opposition movements of the dominant hand were investigated in fourteen right-handed volunteers by functional magnetic resonance imaging (fMRI) techniques. Significant increas...

Microparticle (MP) research is clouded by debate regarding the accuracy and validity of flow cytometry (FCM) as an analytical methodology, as it is influenced by many variables including the pre-analytical conditions, instruments physical capabilities and detection parameters. This study utilises a simplistic in vitro system for generating MP, and through comparative analysis with immuno-electr...

This paper reviews the major contributions to the Motion Planning (MP) field throughout a 35-year period, from classic approaches to heuristic algorithms. Due to the NP-Hardness of the MP problem, heuristic methods have outperformed the classic approaches and have gained wide popularity. After surveying around 1400 papers in the field, the amount of existing works for each method is identified ...

For a graph $$ G = (V, E) with vertex set V and an edge E, function f : \rightarrow \{0, 1, 2, . , diam(G)\} is called broadcast on G. each u \in if there exists v in (possibly, ) such that (v) > 0 d(u, v) \le then dominating The cost of the quantity \sum _{v\in V}f(v) minimum domination number G, denoted by \gamma _{b}(G) A multipacking S \subseteq for every integer r \ge 1 ball radius around ...