The rotational spectra of the monoterpenoids thymol and carvacrol are reported in the frequency range 2-8.5 GHz, obtained with broadband Fourier-transform microwave spectroscopy. For carvacrol four different conformations were identified in the cold conditions of the molecular jet, whereas only three conformations were observed for thymol. The rotational constants and other molecular parameters...

Carvacrol and eugenol, the main (phenolic) components of essential oils of some aromatic plants, were evaluated for their therapeutic efficacy in the treatment of experimental oral candidiasis induced by Candida albicans in immunosuppressed rats. This anticandidal activity was analyzed by microbiological and histopathological techniques, and it was compared with that of nystatin, which was used...

BACKGROUND AND OBJECTIVES Secreted Aspartyl Proteinase (SAP) is one of the main virulence factors in the pathogenesis of Candida. This enzyme is encoded by a family of at least ten genes. Among these genes, the role of SAP1-3 in mucosal infections is evident. This study aimed to investigate the expression of SAP1-3 genes of Candida albicans isolates after treatment with Echinophora platyloba ex...

Background & Aim: Thymus daenensis Celak. is one of the herbal and  perennial medicinal plants belonging to Lamiaceae which grows widely in Isfahan and Chaharmahal va Bakhtiari provinces. All of its floral on aerial part has extensive use in preparing traditional medicines. The major constitutes of Thymus daenensis Celak. are thymol and carvacrol. Since ecolo...

The essential oils of oregano and thyme are active against a number of food-borne pathogens, such as Escherichia coli O157:H7. Carvacrol is one of the major antibacterial components of these oils, and p-cymene is thought to be its precursor in the plant. The effects of carvacrol and p-cymene on protein synthesis in E. coli O157:H7 ATCC 43895 cells were investigated. Bacteria were grown overnigh...

The demand for natural-based products industrial applications is increasing sharply and therefore the search new alternatives to plants traditionally used growing. These alternative can be an important source of bioactive compounds under a circular economy approach. Considering potential future use plant by industry, it necessary assess risk associated with their introduction into ecosystem. Th...

Zataria multiflora (ZM) is a thyme-like aromatic plant in the Lamiaceae family that grows in central and southern Iran. ZM is extensively used as a flavor ingredient in a wide variety of foods and is used as part of popular traditional folk remedies. In the present study, ZM essential oil (ZMO) was obtained from ZM leaves via hydro-distillation and then analyzed by GC-MS (gas chromatography-mas...

Introduction: S. aureus and E. coli are pathogen that can cause persistent infections due to antibiotic resistance mechanisms its ability adhere form biofilm.The search for new agents from natural resources counter microbial biofilm is an urgent priority in healthcare. Objetive: Chemical composition antibacterial anti-biofilm activity of Plectranthus amboinicus essential oil (PAEO) carvacrol we...

INTRODUCTION The present paper summarizes research using animal models to investigate the roles of thermosensitive transient receptor potential (TRP) channels in somatosensory functions including touch, temperature and pain. We present new data assessing the effects of eugenol and carvacrol, agonists of the warmth-sensitive TRPV3, on thermal, mechanical and pain sensitivity in rats. METHODS T...