Nanotechnology has transformed engineering designs across a wide spectrum of materials and applications. Mesoporous Silica Nanoparticles (MSNs) are one the new fabrications nanostructures as medication delivery systems. MSNs have pore sizes varying from 2 to 50 nm, making them ideal for variety biological They offer unique characteristics such tunable surface area, well-defined properties, abil...

Multifunctional magnetic nanoparticles (MNPs) exhibit unique properties, such as remote motion controllability, degradability, and diagnostic imaging, which are typically not shown in nonmagnetic nanomaterials. MNPs remotely controllable via fields offer advantages of high tissue penetrability biocompatibility. In this review, recent advances multifunctional exhibiting characteristic for therap...

Increasingly, nanotechnology has the potential to be applied in disease detection or treatment. Nanotechnology advancements have resulted novel and improved biomedical nanomaterials. Liposomes, polymeric micelles, graphene, carbon nanotubes, quantum dots, ferro ferric oxide nanoparticles, gold nanoparticles (Au NPs), so on are some of most commonly used nanomaterials applications. Because its u...

Although multifunctional upconversion imaging probes have recently attracted considerable interest in biomedical research, there are currently few methods for stabilizing these luminescent nanoprobes with oligonucleotides in biological systems. Herein, a method to robustly disperse upconversion nanoprobes in physiological buffers based on rational design and synthesis of nanoconjugates comprisi...

Polymer nanoparticles (PNPs) were formed from amphiphilic diblock copolymers consisting of a hydrophilic block with pendant polyethylene glycol tosylate (PEG-OTs) groups and a hydrophobic block with pendant terthiophene (TTT) groups. The resulting PNPs were characterized using dynamic light scattering (DLS) and transmission electron microscopy (TEM) to determine size, shape, and polydispersity....

Gold (Au)-decorated iron oxide (Fe3O4), Au/Fe3O4, Janus nanoparticles were fabricated via the continuous route for aerosol Au incorporation with Fe3O4 domains synthesized in an aqueous medium as multifunctional nanoplatforms. The fabricated nanoparticles were subsequently exposed to 185-nm UV light to generate positive charges on Au surfaces, and their activities were tested in computed tomogra...

The ability of peptide-modified gold nanoparticles to target the nucleus of HepG2 cells was explored. Five peptide/nanoparticle complexes were investigated, particles modified with (1) the nuclear localization signal (NLS) from the SV 40 virus; (2) the adenovirus NLS; (3) the adenovirus receptor-mediated endocytosis (RME) peptide; (4) one long peptide containing the adenovirus RME and NLS; and ...

A low toxic multifunctional nanoplatform, integrating both mutimodal diagnosis methods and antitumor therapy, is highly desirable to assure its antitumor efficiency. In this work, we show a convenient and adjustable synthesis of multifunctional nanoparticles NaYF4:Yb, Er@mSiO2@Fe3O4-PEG (MFNPs) based on different sizes of up-conversion nanoparticles (UCNPs). With strong up-conversion fluorescen...