sensory information and to modify existing associations mune function, endocrine function, and more. Long-term deprivation, whether induced experimentally in animals with appropriate deliberation. or induced by disease in humans, invariably leads to Naturally, it is tempting to speculate about the mecha-death. So our relative ignorance regarding the function nistic role of NCS-1 in plasticity. ...

A 25-year-old woman with neither history of trauma nor other previous medical history reported a 2-month history of low back pain. Physical examination revealed no significant abnormality. Conventional abdominal radiography showed the presence of a large, heterogeneous, calcified 10-cm mass in her left lower pelvis (Figures 1A and 1B). Pelvic ultrasonography (US) revealed a large heterogeneous ...

R apid advances in immunobiology, particularly the role of Th1/Th2 cells, have helped to improve our understanding of the inflammatory processes that mediate allergic asthma (1). Interactions between APCs and T cells appear to be the first steps in airway sensitization that ultimately lead to the generation of a Th2-type response. These T cell/APC interactions are characterized by the binding o...

Of the many fields of study that have benefited by monoclonal antibody technology, the analysis of molecules that comprise the mammalian cell surface has been particularly revolution ized. Although conventional serology with immune sera had built an admirable edifice of knowledge about blood group antigens, histocompatibility antigens, and differentiation anti gens in mice and humans, the adven...

Drug induced liver injury (DILI) is a disease caused by xenobiotics (drugs, herbal or diet products) and diagnosed by exclusion of other causes. Some drugs that cause DILI can also cause drug induced autoimmune hepatitis (DI-AIH) by triggering the immune response against liver proteins (1, 2). A 24-yr old male patient in 2015, was admitted to Turkiye Yuksek Ihtisas Hospital, gastroenterology cl...

which are summarized in chapter 2, emphasize the piv-grappling to devise effective vaccines against the human immunodeficiency virus (HIV). otal role in shaping HIV molecular epidemiology of multi-HIV rapidly infects and destroys CD4 ϩ T lymphocytes, ple founder effects during HIV migration among host likely following delivery from peripheral tissues or muco-populations at risk. The nature of H...

Copyright © 2012 Simone Appenzeller et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Autoimmune diseases have a broad spectrum of clinical manifestations. Among them, neurologic involvement, both from the central nervous sys...

Rheumatoid arthritis (RA) is a chronic inflammatory autoim-mune disease that leads to severe joint destruction with deformity and irremediable disability. Early diagnosis of RA and timely initiation of treatments (synthetic and/or biological disease modifying antirheumatic drugs) are both instrumental to limit joint damage and optimize the functional outcome of patients, according to the well-k...

Attenuation of atherogenesis by systemic and local adenovirus-mediated gene transfer of interleukin-10 in LDLr–/– mice. levels of the antiinflammatory cytokine interleukin-10 are decreased in patients with unstable angina. A, Bottiger C et al. Interleukin-10 and tumor necrosis factor gene polymorphisms and risk of coronary artery disease and myocardial infarction. et al. Cuprophane but not synt...