Patients with chronic granulomatous disease are predisposed to fungal infections and are therefore routinely prescribed antifungal prophylaxis. We report a case where acremonium was responsible for causing a cutaneous infection (mycetoma) despite antifungal prophylaxis. Treatment with voriconazole was initiated and the infection gradually resolved. This case highlights the need for careful clin...

BACKGROUND Mycetoma is a chronic granulomatous inflammation of the subcutaneous tissue and usually results due to traumatic implantation of soil organisms. Mycetoma can be eumycotic or acinomycotic in origin. Actinomycetoma is susceptible to a large number of chemotherapeutic agents, but the response is variable and affected by various factors such as extent of involvement, duration of disease,...

Background: Mycetoma is a neglected tropical disease characterized by deformity and disabilities with various medical, health, socioeconomic impacts on the affected communities. The etiological factors associated have not been fully understood, however genetic predisposition inflammation are considered as risk factors. Toll like receptors (TLRs) key players in innate immune response play great ...

Introduction The Caribbean and West Indies are surrounded on 3 sides by endemic zones for most of the major deep mycoses. To the north in the United States there are the southernmost limits of the endemic areas of histoplasmosis and blastomycosis with coccidioidomycosis further to the west in Texas. In Mexico significant numbers of cases of sporotrichosis and mycetoma (madura foot) are seen, wh...

On 19tli Mny, a man of about 30 years of age was admitted to the Ulwar dispensary. His left, foot was very considerably enlarged, and presented numerous diseases, some of which implicated the ankle joint. From these openings proceeded a tlii i discharge, frequently or usually containing black gritty particles. Severe local pain was complained of, and the patient's appearance was worn and somewh...

Background & Objectives: Subcutaneous mycoses comprise a heterogeneous group of fungal infection. They are characterized by development lesions at the site inoculation fungi in subcutaneous tissues. Immunocompromised patients increased risk infections. The main Mycetoma, Chromoblastomycosis, Phaeohyphomycosis, Sporotrichosis followed Rhinosporidiosis, phycomycosis and lacaziosis. This study...

presence of fungal agents in lesions of two patients in tehran was studied. one of them had clinical symptoms of mycetoma in his foot, and the other had a skin infection in his arm. examination of the lesions indicated nocardia asteroides. these patients did not show any evidence of nocardia infection in other parts of the body. negative results were obtained from the cultures of blood and sputum.

Bacterial mycetoma is a neglected disease mainly observed in tropical area countries and typically associated with rural conditions, making its presence in developed countries of temperate climate areas rare. However, we report the first case of an autochthonous mycetoma case in continental France that originated from a new Nocardia species. A Gram-positive filamentous bacterium (OFN 14.177T) w...

BACKGROUND Mycetoma is a chronic infectious disease of tropical and subtropical countries. It is produced by true fungi and actinobacteria. In México, Nocardia brasiliensis is the main causative agent of mycetoma, producing about 86% of the cases; the gold standard for the therapy of mycetoma by N. brasiliensis is the use of sulfonamides which give a 70% cure rate. The addition of amikacin to t...