Citation for published version (APA): Fransson, H., Hedeer, F., Arévalo, C., Carlsson, M., Engblom, H., Ubachs, J., ... Heiberg, E. (2011). Development and validation of a new automatic algorithm for quantification of left ventricular volumes and function in gated myocardial perfusion SPECT using cardiac magnetic resonance as reference standard. Journal of Nuclear Cardiology, 18(5), 874-885. DO...

A new automated method for quantification of left ventricular function from gated-single photon emission computed tomography (SPECT) images has been developed. The method for quantification of cardiac function (CAFU) is based on a heart shaped model and the active shape algorithm. The model contains statistical information of the variability of left ventricular shape. CAFU was adjusted based on...

The assessment of coronary artery calcium (CAC) by ECG-gated non-contrast enhanced computed tomography (NCCT) has achieved widespread clinical acceptance as a measure of coronary atherosclerosis and future cardiac risk. A CAC score of 0 is associated with an excellent prognosis while elevated levels provide incremental prognostic information above and beyond that of conventional cardiovascular ...

PURPOSE Gated single photon emission computed tomography (SPECT) using thallium-201 (Tl-201) has the capacity to evaluate the earlier post-stress (PS) function compared to technetium-99m labeled tracers, and may be more sensitive in detecting transient ventricular dysfunction caused by stress-induced ischemia. The purpose of this study was to assess the prognostic value of functional variables ...

The noninvasive differentiation between ischemic and nonischemic cardiomyopathy is frequently difficult. We examined the clinical value of stress electrocardiographic gated (ECG-gated) single-photon emission computed tomography (SPECT) to identify ischemic cardiomyopathy and detect coronary artery disease (CAD) in 164 patients without known CAD, ejection fraction < or =40% by ECG-gated SPECT, a...

BACKGROUND The aim was to compare the speckle tracking echocardiography (STE) derived systolic longitudinal strain (SL(Smax)) with rest single photon emission computed tomography (SPECT) perfusion imaging (Q(REST)), and to define the optimal cut-offs for SL(Smax) to discriminate transmural scar on contrast-enhanced magnetic resonance imaging (ceCMR). METHODS AND RESULTS In 100 patients with c...

Although stress gated technetium-99m single-photon emission computed tomographic (SPECT) myocardial perfusion imaging (MPI) is useful in differentiating ischemic from nonischemic cardiomyopathy, its prognostic usefulness in this patient population is not well understood. Consecutive unique patients with suspected coronary artery disease who, for clinical indications, underwent technetium-99m re...

The left ventricle myocardium and chamber segmentation in gated SPECT images is a challenging problem. Segmentation is however the first step to geometry reconstruction and quantitative measurements needed for clinical parameters extraction from the images. New algorithms for segmenting the heart left ventricle myocardium and chamber are proposed. The accuracy of the volumes measured from the g...

Different software tools for quantification of myocardial perfusion SPECT (MPS) studies are routinely used. Several perfusion parameters can be computed automatically.  Interpretation of the MPS should start with visual inspection of the rotating planar images, visual analysis of reconstructed SPECT slices and then quantitative analysis to confirm the visual impression. Quantification should be...

The left ventricle myocardium and chamber segmentation in gated SPECT images is a challenging problem. Segmentation is however the first step to geometry reconstruction and quantitative measurements needed for clinical parameters extraction from the images. New algorithms for segmenting the heart left ventricle myocardium and chamber are proposed. The accuracy of the volumes measured from the g...