An Essential MIF-CD74 Signaling Axis in Kidney Tubular Regeneration, with Prospects for 1 Precision Medicine and Pharmacologic Augmentation. 2 3 Running Title: MIF-2/D-DT in AKI 4 5 6 7 Idit Shachar 8 Department of Immunology 9 Weizmann Institute of Science 10 Rehovot 76100, Israel 11 Tel: 972-8-934 4257, Fax: 972-8-934 4141 12 Email: [email protected] 13 14 15 Articles in PresS. Am J...

The recent advent of consensus definitions for acute kidney injury (AKI) has led to improvement in epidemiology of this complex disease and facilitated the development of new diagnostic makers and new therapies. However, important new challenges are also apparent. We still do not really understand why AKI occurs and urgently need to develop new therapies to treat it. Progress in this area will ...