نتایج جستجو برای: namd

تعداد نتایج: 319  

2017
Robert L. Johnston Hans-Joachim Carius Adrian Skelly Alberto Ferreira Fran Milnes Paul Mitchell

INTRODUCTION Neovascular age-related macular degeneration (nAMD) is the leading cause of vision loss among persons aged 65 years and older. Anti-vascular endothelial growth factor (anti-VEGF) treatment is the recommended standard of care. The current study compares the effectiveness of ranibizumab in routine clinical practice in two countries that generally apply two different treatment regimen...

2018
Zhenzhen Yan Haihong Shi Rongrong Zhu Lele Li Bai Qin Lihua Kang Hui Chen Huaijin Guan

Purpose Age-related macular degeneration (AMD) is the leading cause of central visual loss among patients over the age of 55 years worldwide. Neovascular-type AMD (nAMD) accounts for approximately 10% of patients with AMD and is characterized by choroidal neovascularization (CNV). The proliferation of choroidal endothelial cells (CECs) is one important step in the formation of new vessels. Tran...

2015
Michael Karampelas Maria Pefkianaki Angela Rees Navdeep Gill Aachal Kotecha Robin Hamilton Eleni Nikita Praveen J. Patel

INTRODUCTION The aim of this study was to investigate the frequency and duration of missed hospital appointments (MHAs) in a consecutive cohort of patients treated with ranibizumab for neovascular age-related macular degeneration (nAMD) and to assess their impact on outcomes of therapy in a real-world clinical setting. METHODS Retrospective, cross-sectional study of consecutive patients atten...

2015
Christine M. Schmucker Gerta Rücker Harriet Sommer Gianni Virgili Yoon K. Loke Patrick Oeller Hansjuergen Agostini Christoph Ehlken Torben Lykke Sørensen

BACKGROUND To investigate whether treatment as required 'pro re nata' (PRN) versus regular monthly treatment regimens lead to differences in outcomes in neovascular age-related macular degeneration (nAMD). Regular monthly administration of vascular endothelial growth factor (VEGF) inhibitors is an established gold standard treatment, but this approach is costly. Replacement of monthly by PRN tr...

2016
Frank G Holz Ramin Tadayoni Stephen Beatty Alan Berger Matteo Giuseppe Cereda Philip Hykin Giovanni Staurenghi Kim Wittrup-Jensen Andreas Altemark Jonas Nilsson Kun Kim Sobha Sivaprasad

BACKGROUND/AIMS To identify predictive markers for the outcomes of anti-vascular endothelial growth factor therapy for neovascular age-related macular degeneration (nAMD). METHODS AURA was a retrospective, observational, multicentre study that monitored the 2-year outcomes following intravitreal ranibizumab treatment in patients with nAMD. Using stepwise regression analysis, we evaluated the ...

Journal: :JAMA ophthalmology 2017
David J Browning

Polypoidal choroidal vasculopathy (PCV), an oddity shown at fluorescein conferences 35 years ago, is now recognized as a common cause of neovascular maculopathy among thoseolder than50years.1 Its prevalencehasnot increased, but new imaging techniques have revealed its features and ophthalmicconsciousnesshasbeen raised.Randomizedclinical trials that compare treatments, rather than case series, a...

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