Artemisinin (ART) is a natural drug with potent anticancer activities related with Fe(2+) mediated cleavage of the endoperoxide bridge in ART. Herein, we reported that Mn(2+) could substitute for Fe(2+) to react with ART and generate toxic products, inducing a much higher anticancer efficiency. On this basis, we prepared pH-responsive Fe3O4@MnSiO3-FA nanospheres which can efficiently deliver hy...

This article provides an overview on the development of integrated multifunctional nanosystems for medical diagnosis and treatment. In particular, a novel system is developed specifically for achieving simultaneous diagnosis and treatment of cancer. Critical issues are addressed on the architecture and assembly of nanocomponents based on medical requirements: targeted in vivo imaging, controlle...

Controlled release systems of agrochemicals have been developed in recent years. However, the design intelligent nanocarriers that can be manufactured with renewable and low-cost materials is still a challenge for agricultural applications. Lignocellulosic building blocks (cellulose, lignin, hemicellulose) are ideal candidates to manufacture ecofriendly given their low-cost, abundancy sustainab...

Lipid-based nanocarriers have been extensively investigated for drug delivery due to their advantages including biodegradability, biocompatibility, nontoxicity, and nonimmunogenicity. However, the shortcomings of traditional lipid-based such as insufficient targeting, capture by reticuloendothelial system, fast elimination limit efficiency therapeutic efficacy. Therefore, a series multifunction...

Viral contaminations speak to a general medical issue and one of the main sources worldwide mortality. A large portion antiviral medications have low permeability, dissolvability other related physical properties which make them less efficient for treatment. To conquer these constraints, different nanomedicine stages been planned. Nanomaterials offer special physico-chemical that various advant...

In recent years, the interest in sub-micron systems (i.e. nanosystems) in pharmacy has surged. This is in part due to the advantages these systems may provide over existing systems. Designing drug delivery system is challenging in terms of targeting the drug to specific sites. Certain chemicals or therapeutic agents that show success in cell culture fail to produce the same effect in the human ...

Gene therapy has been recently proposed as an effective strategy for cancer treatment. A significant body of literature proved the effectiveness nanocarriers to deliver therapeutic agents 2D tumour...

The skin is known to be the primary intact layer for application of cosmetics and medicines. These nanocarriers, however, can enhance distribution molecules through hair follicles or impart a regulated pattern release by making depots on skin.. moreover, Many challenges may potentially face topical delivery medicaments either healthy diseased skin. This mainly owing strong protection offered ba...

Osteosarcoma, the most common bone cancer, leads to a poor survival rate of patients. Drug targeting employing hydroxyapatite (HAp)-based nanocarriers represents fascinating choice for non-invasive treatment osteosarcoma.