PURPOSE Cell-surface receptor-targeted magnetic iron oxide nanoparticles provide molecular magnetic resonance imaging contrast agents for improving specificity of the detection of human cancer. EXPERIMENTAL DESIGN The present study reports the development of a novel targeted iron oxide nanoparticle using a recombinant peptide containing the amino-terminal fragment of urokinase-type plasminoge...

Folic acid (FA) was conjugated to superparamagnetic iron oxide nanoparticles to develop a tumor specific contrast agent for magnetic resonance imaging (MRI). In this scheme a bifunctional poly(ethylene glycol) (PEG) linker was utilized to both increase biocompatibility and reduce nanoparticle agglomeration. The uptake of nanoparticle-PEG-FA conjugates by folate-receptor (FR) positive MCF-7 cell...

Iron oxide nanoparticles with engineered physical and biochemical properties are finding a rapidly increasing number of biomedical applications. However, a wide variety of safety concerns, especially those related to oral exposure, still need to be addressed for iron oxide nanoparticles in order to reach clinical practice. Here, we report on the effects of chronic oral exposure to low doses of ...

TiO(2) nanobelts were prepared by the hydrothermal growth method. The surface of the nanobelts was coarsened by selective acid corrosion and functionalized with Pd catalyst particles. Three nanobelt samples (TiO(2) nanobelts, surface-coarsened TiO(2) nanobelts and Pd nanoparticle/TiO(2) nanobelt surface heterostructures) were configured as gas sensors and their sensing ability was measured. Bot...

Iron oxide nanoparticle formation in DES was studied in situ across multiple length scales. Initial chloride-containing iron complexes react to form oxygen-rich species which precipitate. Morphology and growth time are defined by solvent composition.

we wish to report a mild and efficient one-pot three-component reaction of an aryl aldehyde, malononitrile and barbituric acid or 4-hydroxycoumarinfor the synthesis ofpyrano[2,3-d]pyrimidine and dihydropyrano[c]chromene derivatives in the presence of iron ore pellet as a natural and reusable catalyst under heterogeneous and green conditions. the present methodology offers several advantages suc...

In this study, a mixed matrix polyethersulfone/iron-nickel oxide nanoparticle nanofiltration membrane was prepared by the solution casting technique. Polyvinylpyrrolidone was also used as a membrane pore former in membrane fabrication. The effect of iron-nickel oxide nanoparticles concentration in the casting solution on the membrane structure and performance was investigated. Scanning...

The aim of this research is to elucidate the size effect of magnetic nanoparticles on the resultant magneto-dielectric properties of polymer nanocomposites at radio frequencies. The block copolymer of [styrene-b-ethylene/butylene-b-styrene] (SEBS) was utilized as a matrix for the templating of magnetic nanoparticles. Surfactant-modified iron oxide (Fe3O4) nanoparticles of various sizes were suc...

A bi-functional nano-composite coating has been created on a porous Nomex® fabric support as a trap for aspirated virus contaminated water. Nomex® fabric was successively dip-coated in solutions containing cysteic acid functionalized alumina (alumoxane) nanoparticles and cysteic acid functionalized iron oxide (ferroxane) nanoparticles to form a nanoparticle coated Nomex® (NPN) fabric. From SEM ...