نتایج جستجو برای: nanopharmaceutical targeting

تعداد نتایج: 148102  

Journal: :Current Biology 1997
Rulang Jiang Thomas Gridley

New technologies are changing the way in which gene targeting experiments are being designed. It is now becoming possible to analyze gene function in defined tissues at specific times during the life of a mouse.

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1994
J H Wilson W Y Leung G Bosco D Dieu J E Haber

We have compared the efficiency of transformation by linear DNA fragments in yeast strains carrying different numbers of homologous targets for recombination. In strains carrying dispersed copies of a target and in strains carrying tandem arrays, the frequency of transformation is proportional to the number of targets. This result is in contrast to previous studies of transformation in mammalia...

2011
Zsuzsanna Kálmán-Szekeres Anna Erdei Adrienn Angyal Zsuzsanna Szekeres Péter Balogh Zsuzsa Neer Eszter Szarka Viktor Virag David Medgyesi Jozsef Prechl Gabriella Sarmay

Journal: :international journal of pediatrics 0
hoda mollaei department of biology, faculty of natural sciences, university of tabriz, tabriz, iran. mohammad khalaj-kondori department of biology, faculty of natural sciences, university of tabriz, tabriz, iran.

the use of animal models in modeling of human genetic disease has many advantages. in some cases, however, this method may not be applicable due to some limitations, such as differences in tissue composition, anatomy and physiology of humans and animals. isogenic human disease models are a population of cells that are selected or engineered to model a specific genetic disease, in vitro. they ar...

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